Преэклампсия в анамнезе: как снизить риск инсульта

Currently, stroke is the third leading cause of death for women in the US compared to the fifth leading cause for men, so it is important to take into account all risk factors associated with the female sex and timely preventive measures .

Women with preeclampsia are 1.5 times more likely to have a stroke before the age of 60 than women without a history of the condition — said Eliza Miller, MD, professor at Columbia University in New York.

In the article estet-portal.com you can find an observational study that examined the effect of acetylsalicylic acid in reducing the risk of stroke in women under 60 years of age with a history of preeclampsia.

Stroke prevention with acetylsalicylic acid

Women aged ≤ 60 years. Of the 83,749 women in the sample, 4,070 (4.9%) had a history of preeclampsia.

During a mean follow-up of 18.1 years, there were 123 hospitalizations for stroke in the preeclampsia group (3.0%, incidence 166 per 100,000 woman-years) compared to 94 (2.3%, 127 per 100 000 women-years) in the group without a burdened history of preeclampsia (p = 0.002). Women with a history of preeclampsia had an increased risk of stroke, even after adjusting for an increased prevalence of risk factors.

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Overall, there was no increase in the risk of stroke before age 60 in the preeclampsia group. But in stratified analyses, women with a history of preeclampsia who regularly took acetylsalicylic acid had a lower risk of stroke before age 60 than those who did not take antiplatelet therapy. This effect was not seen with statins.

Attention to women with a history of advertising

This is not a definitive study, but rather the first attempt to investigate the hypothesis that women who experience hypertensive complications during pregnancy could benefit from primary stroke prevention therapy with acetylsalicylic acid.

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While the current results are too preliminary for clinical decision making, given the results of studies regarding the use of acetylsalicylic acid for the primary prevention of stroke and heart attack in women over 45 years of age, it is prudent to draw the clinician's attention to a cohort of women with preeclampsia in history to reduce the risk of atherothrombotic and thromboembolic complications.

The long-term risk of stroke was lower in women who took acetylsalicylic acid after having had preeclampsia.

Thank you for staying with estet-portal.com. Read other interesting articles in the "Gynecology" section. You might be interested in Risks of late birth

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