The term "carboxytherapy" was introduced only in 1995 by Luigi Parasoni  and has since become very popular in the field of aesthetic medicine, especially used for lipolysis and skin resurfacing. Studies have shown that carbon dioxide improves skin elasticity, blood circulation, helps fight wrinkles, promotes reparative collagen synthesis, and destroys local fat accumulation.  

Typically, carboxytherapy involves the transcutaneous administration of carbon dioxide for therapeutic purposes. Aesthetic medicine technologies use intradermal or subcutaneous injections of sterile carbon dioxide gas, which is delivered into the needle using a standard programmable device, in order to rejuvenate aged skin, eliminate dark circles under the eyes, local fat deposits and stretch marks.

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