To say a new word about hyaluronic acid fillers is not easy, since the cosmetology market can offer the widest variety of such drugs. Nevertheless, the Renaissance company (Italy) managed, in collaboration with the Swedish laboratory, to find and patent a new technology for the production of hyaluronic acid – with nanospheric particles. Thanks to this particle shape, the LEONARDO® filler; easy to administer and has good stability, safe for patients. What is the peculiarity of the filler, and what results it helps to achieve, read on estet-portal.com.
Features of the composition of the filler based on hyaluronic acid with nanospheres
Italian specialists in the field of aesthetic medicine strive for perfect beauty. And the Renaissance company, offering cosmetologists its new line of fillers LEONARDO®, supports the glory of its compatriots, who have long established the right to offer ways to achieve the perfection of appearance. This time we are talking about a new generation filler, in which hyaluronic acid (HA) is contained in the form of nanoparticles. Fillers LEONARDO® represented on our market by Fito Land.
LEONARDO® – this is not just a new filler, but a new concept that provides ease of use, durability and safety. The LEONARDO® filler manufacturing process, based on over 25 years of study and research into HA cross-linking technology, has taken a big step forward. Now the emphasis is on maximum purification of the preparation.
Filler LEONARDO® made from highly purified stabilized HA. The goal of the patented manufacturing technology was to create a safe, dense and durable dermal filler that was easy to inject. This technology includes spherification.
The structure of the HA structure in new generation fillers is as follows. Instead of the traditional cubic/rhomboid HA structure, LEONARDO® HA particles; look like nanospheres of the same size, fully compatible with tissues. The size of the nanospheres is strictly controlled. The spherification technology makes it possible to achieve an ideal location of HA in tissues and controlled disintegration (the duration of filler correction lasts up to 12 months).
Another important feature of the LEONARDO® – it uses less cross-linking agent than usual, resulting in higher product purity with longer shelf life. A large amount of crosslinking agent leads to & nbsp; a strong modification of the HA molecule from its original form. The more cross-linking agent, the higher the risk of adverse reactions (accumulative reactions are possible, which appear only after several procedures). This is because cross-linking changes the natural structure of the HA and makes it different from the human HA. A less cross-linked product is more acceptable in the human body, and provokes less adverse reactions
Amount of crosslinker in LEONARDO® is about 1/10 of the same substance used in other fillers, which guarantees a long-lasting product without using excessive amounts of BDDE. As a result, the HA molecule has a high degree of purification with minimal changes in the structure
Due to the minimum crosslinking agent content, LEONARDO® guarantee a high coefficient of elasticity.
Benefits of hyaluronic acid nanosphere filler
The uniqueness of the LEONARDO® filler, due to the peculiarities of its manufacturing technology, lies in the fact that it combines all the advantages of monophasic and biphasic fillers based on hyaluronic acid.
|
Monophasic fillers |
Bi-Phase Fillers |
|
Smooth feeling (comfort for doctor and patient) Homogeneous consistency Ease of insertion into the skin Even and homogenous distribution in tissues High ductility
|
Identical HA particle size Controlled decay Correction duration High stability Biocompatibility and Safety Low degree of cross-linking (1/10th compared to traditional monophasic) |
LEONARDO® belongs to a new generation of fillers that combines the best of two categories without belonging to either.
New generation nanospheric fillers based on hyaluronic acid
LEONARDO® consists of two products that provide volume and harmony for any kind of contour correction. Fillers are safe, durable, tissue compatible and cost effective.
Leonardo Flair. It is a product of wide application, soft and elastic. It is designed to correct fine and medium wrinkles, restore contours.
Drug characteristics:
HA microspheres: 350 m;
Depth of insertion: superficial and middle dermis;
extrusion group (push-out force): 20;
osmolarity: 200 – 500 mOsmol/kg
viscosity: 110,000 – 150,000 cPa
elasticity: 500 – 700Pa
pH: 6.0 – 7.5
endotoxins: < 0.5 EU/ml
volume: 1ml (20mg/ml);
needles: 2 pcs (27 G).
Filler application example
Leonardo Genius. A denser product designed to correct deep wrinkles and folds, increase lip volume, facial volumetry.
Drug characteristics:
HA microspheres: 750 m;
Depth of insertion: medium and deep dermis;
extrusion group (push-out force): 26.5;
osmolarity: 200 – 500 mOsmol/kg
viscosity: 120,000 – 200,000 cPa
elasticity: 500 – 700Pa
pH: 6.0 – 7.5
endotoxins: < 0.5 EU/ml
volume: 1ml (20mg/ml);
needles: 2 pcs (27 G).
Filler application example
Fillers comply with Medical Device Directive 93/42 / EEC, CE certified according to ISO 13485. BDDE Cross-Linking Degree: ≈ 1%.
The procedure for the introduction of LEONARDO® fillers, presented on our market by Fito Land, gives patients an excellent result in the correction of age-related facial changes, while guaranteeing the safety of the procedure and the durability of the effect obtained.
Share:
Add a comment