Cicatricial lesions of the skin remain an urgent problem when patients turn to cosmetologists, despite the constant improvement of methods and means in aesthetic medicine. It is possible to achieve success in the correction of cicatricial deformities only on the basis of an individual approach, since in each case it is important to take into account the peculiarities of the location and age of the scar, the gender and age of the patient, the somatic background, and many more factors. The most successful results in the correction of atrophic scars can be achieved by combining various hardware, injection and cosmetic techniques. estet-portal.com proposes to consider the possibilities of anti-scar therapy, which are provided by the combination of hardware methods with the injection of Meso-Wharton P199™.
Features of atrophic scars on the skin
Specialists agree that the likelihood of atrophic scarring on the skin is due to various reasons. Most often, atrophic scars occur for the following reasons:
- injuries, cuts, wounds;
- burns;
- consequences of acne;
- after surgery.
One particular form of atrophic scarring of the skin is striae (band-like atrophy of the skin), which appears due to stretching of the skin due to too intensive growth of the body during puberty, during pregnancy or during rapid weight gain (including in athletes who increase muscle mass). mass).
The peculiarities of striae are that they are an atrophic process that develops in the dermis and hypodermis with a decrease in the number of collagen and elastin fibers, as well as fibroblasts that synthesize them. With age, the processes of atrophy only worsen, making the severity of striae even stronger.
Given the reasons for the formation of atrophic scars, complex therapy should include a set of actions that would help smooth out external retraction, prevent further atrophic processes and stimulate reparative processes in the skin.
Methods for correcting atrophic scars and their combinations
The following methods are currently used to correct atrophic cicatricial deformities:
- cosmetic – glycol, TCA or phenol chemical peels;
- injection – microneedling, injection of preparations based on collagen, hyaluronic or polylactic acid;
- hardware – microdermabrasion, radio frequency therapy, laser treatment;
- surgical – undercutting of the scar bottom, lipofilling.
One of the effective combinations in the treatment of atrophic scars was the combination of fractional photothermolysis and an injectable drug that directly stimulates regeneration processes – Meso-Wharton P199™.
The essence of this combination of techniques is that the action of the laser activates reparative processes in the skin through predictable damage. To translate reparative healing into physiological regeneration, with the formation of full-fledged skin structures, the next step is injection procedures using the drug Meso-Wharton P199™, whose mechanism of action is to stimulate the activity of "the skin's own stem cells"; – basal keratinocytes and mesenchymal stem cells, which ultimately leads to the synthesis of the required amount of structural components of the epidermis and dermis and minimizes the manifestations of atrophy.
Mechanism of action of Meso-Wharton P199™ in the treatment of atrophic scars
Renewal of cellular structures, restoration of cell vitality and regenerative processes in skin tissues are carried out due to the constantly ongoing processes of division and differentiation of "skin stem cells". It is they who are ultimately responsible for preventing and reducing the severity of atrophic processes in the dermis and, in general, for achieving an aesthetic result. Meso-Wharton P199™ contains a specific regulatory peptide, Wharton Jelly Peptide P199™ – synthetic analogue of a human polypeptide. Thanks to the activity of this peptide, the mobilization of "the skin's own stem cells" occurs, their proliferation and differentiation into keratinocytes and fibroblasts.
Activation of skin stem cell activity with Meso-Wharton P199™ promotes the synthesis of the required amount of structural components of the epidermis and dermis and minimizes the manifestations of atrophy
Regulatory peptide Wharton Jelly Peptide P199™ allows you to activate the division of skin stem cells and create optimal conditions for their division and differentiation. In addition, Meso-Wharton P199™ provides almost complete restoration of the skin after laser exposure.
Combined correction of atrophic scars, based on the use of laser treatment and injections of Meso-Wharton P199™, allows you to get an aesthetically acceptable result and improve the quality of life of the patient.
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