With what envy everyone around looks at people with an accelerated metabolism. After all, they do not need to take care of their figure so much, controlling every calorie.
Many say it's luck, but we understand that the metabolic rate depends, firstly, on genetic predisposition, and secondly, on the way of life. Enzymes play an important role in the regulation of metabolism. And one of the most important is 5'AMP-activated protein kinase (AMPK).
Read on estet-portal.com how to speed up your metabolism with it without harming your health.
How to speed up metabolism: helper enzymes
Adenosine-5-monophosphate-activated protein kinase (AMPK) is an enzyme that is known as the "master regulator of energy metabolism".
It acts as an energy sensor inside our cells, helps to stabilize the balance between energy production and consumption, helps maintain homeostasis, stimulates weight loss, reduces inflammation, increases insulin sensitivity.
Researchers believe that AMPP activity may depend on genetic predisposition, lifestyle, and also decreases significantly with age.
Thus, ensuring the normal functioning of this enzyme makes it possible to always stay in shape and preserve beauty and youth for as long as possible.
Read also: Metabolism: changing obesity to slimness
How AMPP affects the human body
AMPP is found in all tissues of the human body, but its concentration is especially high in the brain, liver, fat cells and skeletal muscles, which is associated with an increased intensity of metabolic processes in them. The task of this enzyme – properly allocate energy resources. To do this, AMPP, by acting on the hypothalamus, can affect appetite, body temperature, hormone synthesis and many other processes.
Thus, the main functions of this enzyme are:
• Regulation of energy consumption. Increased caloric intake reduces appetite and increases energy intake, body temperature and perspiration;
• maintaining a normal weight. AMPP enhances muscle glucose uptake;
• Reducing inflammation. This enzyme has anti-inflammatory potential as it promotes antioxidant activity, protecting the body from aging-accelerating factors such as poor nutrition, chemical/toxic exposure, and chronic stress;
• increased insulin sensitivity. AMP-activated protein kinase is the main cellular regulator of lipid and glucose metabolism;
• improvement of physical performance. During exercise, AMPP increases glucose uptake and fatty acid oxidation.
Some research suggests that AMPP may support cell renewal and activate autophagy. This suggests that this enzyme plays an important role in preventing the aging process.
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How to quickly and effectively increase the activity of the AMPP enzyme
Energy depletion (or lack of energy) stimulates AMPP activity. This means that one of the best – this is "favorable" stress, namely:
• intense physical activity;
• exposure to cold, hardening;
• calorie restriction and fasting.
Calorie restriction and fasting are two of the most powerful ways to enhance AMPP signaling. Adiponectin is secreted in fat cells to signal a low energy status, resulting in an increase in AMPP.
Foods high in antioxidants enhance AMPP activity.
Studies show that foods high in antioxidants, especially polyphenols, help activate AMPP. Especially such products are useful for those who are at risk of hyperlipidemia, atherosclerosis and diabetes.
High-antioxidant, high-polyphenol foods include:
• fresh vegetables such as leafy greens, broccoli, artichoke and green beans;
• green tea;
• coffee and cocoa;
• berries such as blueberries, blackberries, raspberries, blueberries;
• grapes;
• olive oil;
• pomegranate juice;
• apples;
• red wine;
• bow;
• herbs and spices such as cinnamon, turmeric, etc.
Also stimulates AMPP activity Metformin, an antidiabetic drug used to treat type 2 diabetes. The drug activates the enzyme in the liver cells, resulting in fatty acid oxidation, suppression of lipogenic enzymes, and activation of glucose uptake by fat cells.
Some pharmaceutical companies produce supplements containing this enzyme. However, there is no evidence to support their effectiveness.
Thus, maintaining the activity of AMPP in a natural way helps to accelerate metabolism, preserve youth and health for many years.
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