It is estimated that around 20% of all adult males suffer from erection problems, this figure rises to 50% in men aged 40 and over.
The etiology of erectile dysfunction is multifactorial, including various organic and psychogenic factors, but for most of these men, their problem is vasculogenic in nature and is associated with the functioning of the endothelium and smooth muscle cells that line the arteries, including the penis, and the gradual development of fibrosis penis.
(known as PDE5 inhibitors) have been very successful, however, they do not address the root cause of erectile dysfunction. On estet-portal.com read about new approaches to the treatment of erectile dysfunction. Physiology of erection mechanism and pathogenesis of erectile dysfunction
Erectile tissue consists of smooth muscle lined with endothelium and divided by fibrous bands or trabeculae into a series of small compartments or cavernous spaces.
Penile Erection – it is a neurovascular phenomenon that leads to relaxation of the cavernous smooth muscles, which reduces the pressure inside the penis, allowing blood to enter and fill the sinusoids, which leads to the expansion of the penis. At the same time, the emissary veins constrict, causing an erection as the blood stays in the penis rather than back into the bloodstream.
Medications that inhibit PDE-5 promote relaxation of the smooth muscles of the penile vessels.
Problems with erection may have an organic or psychogenic cause. However, in practice, most patients suffering from erectile dysfunction have a mixed etiology: an organic cause that is usually exacerbated by anxiety and stress.
Impotence or Erectile Dysfunction: Treating Impotence Male Sexual Rejuvenation: Shockwave Therapy
The goal of male penile rejuvenation is to break this vicious cycle of erectile dysfunction by improving endothelial function.
A minimum of 6 shock wave sessions is recommended to achieve results, and an energy flux density level of around 0.09 mJ/mm2 is safe and effective.
Extracorporeal shock wave therapy or shock wave treatment induces a pro-inflammatory response in the tissue. It is assumed that the body responds to this by increasing blood circulation and metabolism in the affected area, which, in turn, accelerates its own healing processes and leads to angiogenesis.Read the latest articles in
Telegram Intracavernous stem cell injections, PRP
As in many other areas of medicine, it has been suggested that intracavernous injections of stem cells and PRP can rejuvenate the erection mechanism.
Commercially, due to strict regulatory restrictions on laboratory cultured stem cells, intracavernous stem cell injections are not widely available in Europe and are more commonly used in places such as the Middle East and the US. As an alternative, many clinics offer PRP injections for sexual rejuvenation.
From a safety point of view, PRP and
are safe for injection into the cavernous bodies. They do not adversely affect the mechanism of erection and do not increase the risk of malignant neoplasms. Unfortunately, the evidence base for the effectiveness of these treatments is still lacking. Intracavernous injection of botulinum toxin
Botulinum toxin is also suggested for use in the treatment of erectile dysfunction. The hypothesis is that since cavernous smooth muscle relaxation is an integral part of erectile development and botulinum toxin is a strong inducer of smooth muscle relaxation, it may therefore be effective in treating erectile dysfunction.
Botulinum toxin treatment is still very new and should still be considered experimental.
Based on the current evidence base, safety profile, and ease of administration, shock wave therapy is the most reliable and promising non-surgical treatment option for erectile dysfunction.
Modern approaches to the treatment of erectile dysfunction
Add a comment