A new approach in the treatment of human papillomavirus infection

Today, there are convincing data that prove the importance of human papillomavirus infection in the development of oncological pathologies. According to the results of epidemiological studies, it turned out that 99% of cases of cervical cancer were found in women infected with the human papillomavirus. Also, the virus can provoke the development of oncological pathology of the rectum and oral cavity. How does human papillomavirus infection occur? What is the effective treatment for human papillomavirus infection?

Mechanism of human papillomavirus infection

Virus infection occurs in the presence of microtraumas. Through damage to the skin and mucous membranes virus penetrates and forms reservoirs in the basal plate of the epithelium, notes estet-portal.com   Virus replication and assembly of parts of the virus occurs in differentiated cells of the superficial layer.

Mechanism of human papillomavirus infection:

• When the virus is in the basal layer and is not detected by colposcopy, histology and cytology, this condition is called asymptomatic carrier.
• It is believed that at this time the virus is in the cell in an episomal state in a small number of copies. Further, the clinical stage of the disease may develop.
• The subclinical stage is characterized by the detection of the virus during colposcopy, histology and cytology. This stage is difficult to diagnose because the changes are not visible visually.
• But the clinical stage (manifest) in the form of invasive cancer or exophytic warts is distinguished by the presence of clinical symptoms and the possibility of diagnosing the process without additional research methods.

Basic approaches in the treatment of human papillomavirus infection

In the presence of papillomavirus infection, nonspecific immunity factors are characterized by a significant increase in the relative number of the natural cell population – killers with insufficient functional activity.

Therefore, a combined approach is considered the most effective in the treatment of human papillomavirus infection.

At the same time, local removal of genital warts is carried out against the background of systemic antiviral and immunomodulatory treatment, however, in many cases, the treatment of papillomavirus infection does not bring the desired result, since it is not accompanied by elimination of the pathogen.

This dictates the need to search for new safe and highly effective drugs in the treatment of human papillomavirus infection.

A new substance in the treatment of human papillomavirus infection

Allokin – alpha. This is a drug of natural origin with antiviral immunomodulatory action. Active ingredient – cytokine-like peptide alloferon – 1. When the drug is administered subcutaneously, the drug induces the synthesis of endogenous IFN, and also activates the systems of natural cells – killers. A study was conducted on the effectiveness of this drug in the treatment of human papillomavirus infection. 60 patients of different sex were examined.

According to the results of the study, it was revealed that Allokin – alpha has a high antiviral effect.

Against the background of the use of the drug, a decrease in the number of vegetations was noted in 24 patients. 3 months after complex therapy, human papillomavirus DNA was not detected in 26 out of 30 patients. Clinical remission was noted in 28 out of 30 patients. At the same time, no adverse reactions were observed in any patient during the treatment of papillomavirus infection. The research results allow us to consider cytokine-like peptides alpha – 1 as an effective means of combating  papillomavirus infection.