The treatment of skin and soft tissue infections is a serious problem of modern medicine, given the global increase in resistance of gram-positive flora to traditional antibiotics, in particular methicillin-resistant strains of staphylococci, and stratification of the severity of skin and soft tissue infections is an important component in choosing treatment tactics.
Find out in the article on estet-portal.com
- approaches to the classification of skin and soft tissue infections
- prescribing antibiotics for skin and soft tissue infections
- surgical strategy for the treatment of skin and soft tissue infections
Approaches to the classification of skin and soft tissue infections
Mild types of infections of the skin and soft tissues include typical phlegmon / erysipelas without purulent foci; to infections of moderate severity ─ typical phlegmon / erysipelas with the presence of systemic signs of infection; severe skin infections ─ failure of oral antibiotics, systemic signs of infection, immunosuppression, or clinical signs of deep tissue involvement (skin detachment and necrosis, hypotension, and signs of organ dysfunction).
Follow us on Instagram!
Treatment of skin and soft tissue infections is achieved with a combination of surgery and antimicrobial therapy. For example, subcutaneous abscesses are treated primarily with surgical treatment (opening and draining) and only for patients who do not respond to initial interventions, additional antibacterial therapy is prescribed.
Prescribing antibiotics for skin and soft tissue infections
spread of the disease or abscesses in areas difficult to drain, with rapid progression of the infection, signs of systemic diseases, severe comorbidities, or immunosuppression. The leading component of the empiric choice of antibiotic depends on the clinical manifestations of skin and soft tissue infections. In most cases where Gram-positive flora is the likely cause of skin infections and MRSA is not suspected, penicillins, cephalosporins, clindamycin, or trimoxazole are used.
Where the infection is polymicrobial in nature (infections in the immediate vicinity of the genital tract, rectum, bite wounds, etc.),antibiotic treatment should cover a wide range of pathogens.
Under these conditions, antibacterial therapy may include beta-lactam antibiotics protected by inhibitors, drugs with increased activity against gram-positive strains, such as glycopeptides, carbapenems, oxazolidinones, III-IV generation fluoroquinolones and new drugs (tigecycline, ceftaroline, etc.), in combination with proper wound care and early surgical intervention, which occupies a leading place in the treatment of skin and soft tissue infections.
Ptosis of the upper eyelid: diagnosis and treatment AF Cardona et al. proved that infections of the skin and soft tissues are an important cause of morbidity and mortality among hospitalized patients and
become a serious challenge for clinicians. Although uncomplicated forms of ICMT are successfully treated on an outpatient basis, severe forms of infection that spread to the subcutaneous tissue, fascia, or muscles require complex multi-vector treatment. Early diagnosis, selection of appropriate antimicrobials and timely surgical intervention are the keys to successful treatment.
Postoperative wound infections are an important component of skin and soft tissue infections. Gram-positive organisms such as Staphylococcus aureus and Streptococcus pyogenes
are the dominant organisms found early in the infection process, while Gram-negative organisms appear in chronic wounds.
What determines the cost of breast augmentation
Methicillin-resistant Staphylococcus aureus (MRSA) is a potential source for possible generalization of the infection, requiring aggressive antibiotic therapy and surgical treatment.
Alternatives such as telavancin, daptomycin, linezolid, ceftaroline, dalbavancin, oritavancin, and tedizolid have been successfully used to treat severeMRSA . Surgical strategy for the treatment of skin and soft tissue infections For
purulent infections of the skin and soft tissues, the treatment strategy for milder formsis to open and drain; for moderate disease with systemic signs of infection other than the above,
add oral antibiotics, for severe cases of infection, including failure after opening and draining with addition of oral antibiotics, or when systemic signs of infection are present (temperature > 38 °C, tachycardia > 90 beats/min, tachypnea > 24/min, changes in blood counts with a shift to the left) perform repeated surgical interventions, and also switch to parenteral administration of antibiotics. How effective is the use of compression stockings?
Defects of the skin and soft tissues, known as pressure sores and ulcers due to compression injury, are localized areas of damage to the skin only or involving deeper tissues. The range of treatment for such skin lesions includes the use of dressings impregnated with drugs with antimicrobial properties, antiseptics, as well as systemic antibiotics.
Treatment of surgical infection of the skin and soft tissues focuses on surgical control of the source of infection and antimicrobial therapy, taking into account individual patient risk factors and multidrug-resistant bacterial strains.
More useful information on our YouTube
-channel:
Share:
Add a comment