Выбор препарата для лечения грибкового поражения стопы: результаты исследований
Dermatophytes

— is a collective term for the most common type of fungus that causes skin and nail infections. Dermatophytes have the ability to penetrate keratinized tissues (skin, hair and nails). The infection is usually limited to the outer layer of the skin (epidermis). Skin between fingers — frequent site of fungal infection. The skin may become white and macerated, and blisters may form. They can rupture and spread to other areas of the foot, especially the sole, where the area becomes red and moist. In addition, spots with hard thickened skin appear on the soles, heels and sides of the foot. This may cause cracking of the skin.

Fungal nail infections (onychomycosis) can affect the entire nail plate, and one, several, or all of the toenails can be infected at the same time. Nails often appear discolored and may thicken and change in texture.

Fungal infections

of the nail are often associated with a skin infection, in which case they can be a source of reinfection if only the skin is treated. In the article estet-portal.com you can read in detail the results of the Cochrane systematic

review of the effectiveness of modern antifungal medicines

. Treatment of fungal skin lesions of the foot: what is effective

Of the 144 studies identified, 67 studies met the inclusion criteria. All antifungal compounds have shown some success in treating fungal infection. The best results have been seen with allylamines, and there is little evidence that butenafine may be as effective.

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Azoles have also been shown to be effective against fungal infection and patients should be informed that using an azole cream for 4 weeks may give better results than using it for one week.

There is limited evidence of the effectiveness of tea tree oil in skin fungal infections. Azoles may also be more effective than tolnaftate, but they are no more effective than undecanoic acid.

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There is little evidence that topical antifungals are effective in treating onychomycosis or fungal nail infections. There is some evidence that ciclopiroxolamine and butenafine are effective, but they must be used daily for extended periods (at least one year).

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Amorolfine and butenafine may be much more effective than ciclopyroxolamine and tea tree oil, but only a few observations are available.

Thus, the modern arsenal of drugs allows you to get rid of the problem of fungal infections of the skin and nails of the foot. A competent choice of the drug is a decisive factor in the success of treatment.

Thank you for staying with estet-portal.com. Read other interesting articles in the "Dermatology" section. You may be interested in

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