Obesity − it is a global epidemic and its prevalence has increased dramatically in children by 47% and in adults by 28% from 1980 to 2013. By 2030, 20% of the world's adults are projected to be obese and another 38% overweight, if current trends continue.
Find out in the article on estet-portal.com the appearance of which dermatological and cosmetic diseases provokes obesity.
- Obesity as an epidemic of our time
- The association of obesity with melanoma and acne
- Studying the effect of obesity on the frequency of acne and melanoma
Obesity as an epidemic of our time
Approximately 300 million people worldwide are overweight or obese, which is a major public health problem. This is due to the fact that obesity, as a multifactorial disease, is associated with numerous comorbidities, such as cardiovascular disease, cancer, diabetes mellitus, hypertension, osteoarthritis, and sleep apnea.
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Obesity also leads to metabolic changes that have dermatological manifestations, but these have received minimal attention and have not been extensively studied. Recently, researchers have shown interest in studying the role of obesity in psoriasis. However, this disease is also associated with other dermatoses.
The association of obesity with the occurrence of melanoma and acne
Melanoma is the most deadly form of skin cancer and its incidence continues to increase worldwide much faster than any other type of solid cancer. Acne is also one of the most common skin diseases, and the eighth most common worldwide, according to epidemiological data.
An earlier meta-analysis assessed the association between obesity and the risk of melanoma. This is a case-control study. lasted from 1984 to 2008.
Because lifestyle factors have changed in recent years, scientists believe it is important to re-run the meta-analysis using the latest reports, which will be the best indicators of the current time. In addition, no meta-analysis has yet been conducted to examine the association between obesity and the risk of developing acne and melanoma.
Studying the effect of obesity on the incidence of acne and melanoma
Scientists have been doing research for the past 8 years that has linked body mass index and obesity rates to very common dermatological diseases such as melanoma and acne. A comprehensive information search was performed using the PubMed database to identify relevant literature, estimate the incidence of melanoma and acne in obese and overweight individuals.
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The relationship between elevated body mass index and melanoma incidence has been investigated in the past. This time, the researchers aimed to investigate associations between obesity and dermatological diseases, using new epidemiological data to explore and confirm preliminary results.
A meta-analysis included 2304 patients with melanoma and 2468 controls to study the impact of obesity on the course of melanoma. All five studies with a case-control design covered participants of different ages - both men and women.
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For the acne study, the meta-analysis included a total of 2296 participants of all age groups − 983 acne patients and 1313 controls. Both men and women were involved in the research.
Relationship between obesity and melanoma
Five studies were included to investigate the relationship between obesity and risk of melanoma. Two studies reported a higher risk of melanoma in people who were obese and overweight (body mass index > 25 kg/m2), while the other three showed no significant effect.
Relationship between obesity and acne
Four studies were included to assess the relationship between obesity and acne risk. One study showed a higher risk of acne in obese and overweight people, while the other three showed no significant effect.
In total, 2304 melanoma patients and 2468 controls, 983 acne patients and 1313 controls from 5 and 4 case-control studies were included in the meta-analysis. The results showed a weak positive association between an increase in body mass index (> 25 kg/m2) and melanoma and a null association between an increase in body mass index (> 25 kg/m2) and the development of acne.
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The result of the first meta-analysis showed that with an increase in body mass index, there is an increased risk of developing melanoma. This result is consistent with previous meta-analyses. The second meta-analysis showed no significant associations between obesity and acne. However, as this is the first meta-analysis of this comorbidity, larger studies are needed to assess the relationship between elevated body mass index and acne incidence.
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