The most popular injection procedures: what are the differences

Injection procedures for the correction of age-related changes in the face – such as mesotherapy, biorevitalization and bioreparation – are the most popular among patients due to their popularity. However, the effectiveness of these procedures and, accordingly, patient satisfaction, is determined by the correct assessment of the indications for their implementation.

The choice of  patients for each of the procedures depends on the age characteristics of the skin and its type, various concomitant conditions, and even on what is planned to be obtained as a result of the course of injections. The bioreparation procedure in a certain sense combines the properties of other injection courses, and when it is carried out with Meso-Wharton™ F199 and Meso-Xanthin™ F199, it even has certain advantages, which you can read about on estet-portal.com.

Biorepair advantages over other injection procedures

Mesotherapy, biorevitalization and bioreparation do have many common features. Therefore, they are often confused not only by patients, but even by cosmetologists who have just begun to master injection procedures.

Mesotherapy	Intradermal and subcutaneous administration of cocktails of various preparations, which are selected depending on the skin problem that the patient applied for
Biorevitalization	Intradermal administration of unmodified hyaluronic acid when there is a violation of its physiological concentration in skin tissues
Bioreparation	Intradermal administration of preparations containing unmodified hyaluronic acid plus active substances – peptides, amino acids, vitamins, etc.

Injection procedures are carried out with thin needles, with the help of which the necessary substances are delivered directly to the various layers of the soft tissues of the face and body. The most popular mesotherapy techniques are nappage techniques, which allow the injection of drugs into the epidermis and dermis.

Deep nappage or infiltration allows the drug to be injected to a depth of more than 4mm, depending on the localization of the drug administration technique.

The main difference between mesotherapy and biorevitalization is the composition of preparations for administration and their consistency.

In addition to the components in mesococktails that perform a therapeutic function, their main deliverer to the tissue is hyaluronic acid, which in mesococktails is always unstabilized, of low molecular weight. This characterizes mesococktails as liquid preparations that have a fairly quick effect, but not very long and do not have a cumulative effect.

Preparations for biorevitalization and bioreparation also contain hyaluronic acid in their basis, however, in such cocktails, unlike mesococktails, it has a higher molecular weight, more than 1000 kDa. This molecular weight of hyaluronic acid in the composition makes the preparations more viscous, gel-like, which excludes their introduction to nappage techniques.

Biorevitalizants are introduced mainly into the dermis by papules of various diameters or microinjections, they have a prolonged action and a cumulative effect.

Indications for various injection procedures

Mesotherapy	Main indications for mesotherapy – these are violations of the function of the epidermis (dyschromia, xerosis, etc.), inflammatory processes in the dermis (acne), excessive fat deposits, decongestant vascular therapy.
Biorevitalization	Decrease in turgor, dryness and dehydration, fine superficial wrinkles
Bioreparation	Indications for bioreparation, as in mesotherapy, vary from the effect of components in the preparation other than hyaluronic acid. There may be: inflammatory processes (acne, rosacea); disorders of seboregulation; pigmentation; correction of fatty deposits on the face; normalization of vascular function of all vascular systems; restoration of the normal function of collagen formation and much more.

The peculiarity of preparations for bioreparation is that they contain high molecular weight hyaluronic acid, which provides an intercellular framework characteristic of healthy skin and is a deliverer of therapeutic components. Thus, the effect of bioreparation lasts longer and may have a pathogenetic effect on the disease.

Bioreparation with Meso-Wharton™ F199 and Meso-Xanthin™ F199 from Emet™ allows the skin to create a reserve of active substances that will be gradually released and promote intensive skin renewal.

Based on Meso-Wharton™ F199 and Meso-Xanthin™ F199 are unique polypeptides, as well as amino acids, trace elements, vitamins, which create all the conditions for an "intensive" skin therapy for various indications. 

Characteristics	Mezovarton	Mesoxanthin
Age Selection of Patients	A unique drug for the intensive care of aging skin in patients with severe signs of structural loss and, as a result, an increase in the surface area of ​​the skin, a decrease in its elasticity and turgor	A unique drug for intensive care of patients whose skin is prone to damaging factors (inflammation, insolation, smoking, as well as intensive care for problem skin (in the complex treatment of acne, rosacea)
Main action	Creates optimal conditions for migration, proliferation and differentiation of the skin's own stem cells into healthy young cells of the epidermis and dermis, which completely restores the structure of young skin in aged patients	Has a non-specific anti-inflammatory effect, normalizes pigmentation, protects and restores cellular DNA and skin cells themselves from the effects of damaging factors, which is clinically expressed in the alignment of complexion and the appearance of "radiance"; skin, elimination of morphological elements of acne and rosacea, normalization of sebum secretion, narrowing of pores
Main components	Polypeptide "Wharton Jelly Peptide P199" high molecular weight hyaluronic acid; amino acids; vitamins; growth factors;	carotenoid "Fucoxanthin F199" high molecular weight hyaluronic acid; amino acids; vitamins; growth factors;
Results of bioreparation with the preparation	Restoration of the structure of young skin in patients of the older age group: thickening of the epidermis and dermis, reduction of the area of ​​the skin flap, restoration of the intercellular framework, elimination of age-related dyschromia	Restoring the structure of a "healthy" skin in patients of different age groups: alignment of complexion, the appearance of "radiance"; skin, elimination of morphological elements of acne and rosacea, normalization of sebum secretion, narrowing of pores
Course of bioreparation procedures	From 4 to 8 sessions with an interval of 7-14 days, the duration of the effect obtained is 12 months	From 4 sessions with an interval of 7-10 days, the duration of the effect depending on the indications is 8-12 months

Meso-Wharton P199 and MesoXanthin F199 combined intensive therapy can be prescribed by a doctor according to indications and is carried out in a course of 4 + 4 treatments, 2 + 6 or 6 + 2 at intervals of 1-2 weeks.

Hyaluronic Acid at Meso-Wharton™ F199 and Meso-Xanthin™ F199 has a high molecular weight (more than 3 million Da), which makes it possible for the preparations to maintain the optimal hydrobalance of the skin for a longer time and not contribute to the active stimulation of the "damaged" skin. or "aged" skin structures.

Results of bioreparation with Meso-Wharton™ F199 and Meso-Xanthin™ F199 are noticeable after the first procedure, and a full planned course can solve many of the patient's aesthetic problems.