Diagnosis of bromhidrosis: what diseases should be excluded

Bromhidrosis – is a chronic condition in which the skin emits an excessive odor, usually unpleasant.

Bromhidrosis is largely determined by the secretion of the apocrine and sometimes eccrine glands, and can significantly impair a person's quality of life. It is very important for a doctor to establish the cause of bromhidrosis in order to prescribe the correct treatment.

To treat this disease, medical, hardware and surgical techniques, read more about it at estet-portal.com in this article.

• Bromhidrosis: where does bad smell come from
• Diagnosis of bromhidrosis: what diseases should be excluded
• Bromhydrotreatment methodsfor

Bromhidrosis: where does bad smell come from

• Apocrine bromhidrosis is the most common form of bromhidrosis and should be distinguished from the less common eccrine bromhidrosis.

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Several factors contribute to the pathogenesis of apocrine bromhidrosis. Bacterial degradation of apocrine secretions results in the formation of ammonia and short-chain fatty acids with their characteristic strong odors.

 

 

Excessive secretion from the apocrine or eccrine glands, which becomes foul-smelling when bacteria are destroyed, is the main cause of bromhidrosis.

Inadequate hygiene and medical or dermatological conditions associated with hyperhidrosis or bacterial overgrowth may further contribute to its development.

The axillary bacterial flora has been shown to create a characteristic axillary odor by converting odorless precursors in sweat into more odorous volatile acids that are released by the action of the bacterial enzyme Corynebacterium.

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• Eccrine Bromhidrosis

Under certain circumstances, the secretion of the mucous membrane, which is usually odorless, acquires an unpleasant odor and causes eccrine bromhidrosis.

Ingestion of certain foods, including garlic, onions, curries, alcohol, certain drugs (eg, penicillin, bromides), and toxins, can also cause eccrine bromhydroz.

Diagnosis of bromhidrosis: what diseases should be excluded

Among the most dangerous diseases to be ruled out in the event of an unpleasant body odor are:

• liver failure (fetor hepaticus), in which there is a characteristic smell of rotten eggs;
• kidney failure accompanied by ammonia smell;
• schizophrenia can also be associated with characteristic body odor;
• trimethylaminuria (smell of fish).

Read also: Non-invasive treatment of hyperhidrosis of any localization

Bromhidrosis often accompanies hyperhidrosis. Therefore, it can develop with obesity, diabetes mellitus and disorders in the thyroid gland psy.

Methods of treating bromhidrosis

There are several treatments for bromhidrosis.

Conservative measures to reduce bacterial flora and maintain a dry environment include improved hygiene and topical therapy.

The use of topical antibiotics such as clindamycin, erythromycin, and benzoyl peroxide, as well as antiseptic soaps, may provide clinical benefit by limiting the growth of contributing bacteria.

The use of antiperspirants, including aluminum chloride, may improve the course of bromhidrosis of apocrine or eccrine origin, especially if hyperhidrosis is one of the factors.

 

 

For patients who want longer-term treatment, several non-surgical treatment options have been developed:

• Nd: YAG laser effective in axillary bromhidrosis;
• The inhibitory effect of botulinum toxin A to reduce sweat production by denervation of the eccrine sweat glands has also been used to successfully treat axillary hyperhidrosis.

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Surgical treatment axillary bromhidrosis has been used in a limited manner in the United States; however, some surgical techniques are more widely used in Asian countries, where this problem is even more acute.

Surgical treatment improves long-term management of bromhidrosis, but is associated with an increased risk of scarring, surgical complications, and the risk of recurrence.

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