Botulinum toxin therapy for reducing the manifestations of age-related changes in the face occupies a leading position in the world, despite the emergence of new anti-aging cosmetic techniques. Usually we are talking about injection procedures using preparations containing type A botulinum toxin. sometimes because of the fear of toxins, sometimes because of intolerance to the drug, or for other fairly objective reasons. In this case, cosmetic products with neuropeptides will come to the aid of the cosmetologist. How they work, and what means will help achieve the effect of botulinum therapy, read on estet-portal.com.

How neuropeptides work in cosmetics

Peptides in cosmetics are very popular today. Sometimes they are credited with truly magical properties of instant skin rejuvenation, although in fact their activity and ability to penetrate the skin depends on many factors – structures, structures, ways of linking amino acids. The biological activity of peptides allows them to regulate some important physiological processes in the body. For example, neuropeptides are able to block neurosynapses and thereby lead to relaxation of mimic muscles. As a result, you can get an effect that is quite comparable with the action of botulinum toxin. It is on this property of neuropeptides that the development of some cosmetic preparations for facial rejuvenation is based.

The most famous of the group of neuropeptides – argireline, sometimes even called botox peptide.

Argireline is a muscle contraction blocker that does not cause paralysis of target muscle cells as botulinum toxin does, but is able to slow down neuromuscular transmission at the sites of exposure to the drug with argireline.

The muscle contraction blocker argireline is part of the EJI ARGIRELIN meso-cocktail. The action of this meso-cocktail is based on the fact that the facial muscles of the face with their distal parts are woven directly into the skin, and if you create a depot of EJI ARGIRELIN in it, then the deposited amino acids disrupt the release of acetylcholine into the intersynaptic gap. As a consequence, the transmission of the neuromuscular impulse is weakened. Non-ejected mediator molecules decompose under the influence of acetylcholinesterase and do no harm.

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Results of the administration of drugs with neurotoxins: the effect of EJI ARGIRELIN

EJI ARGIRELIN, presented on the Ukrainian market by the distribution company I-Сosmetolog, does not include live toxin cultures and is not capable of causing target cell paralysis, and therefore belongs to local muscle relaxant agents. If we compare its effectiveness with the preparation of botulinum toxin, then to achieve the inhibition of neuromuscular transmission, which can be obtained with a single injection of botulinum toxin, 10 sessions of injection of neurotoxin will have to be carried out. However, slow-acting facial injections with peptides have their advantages.

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The use of EJI ARGIRELIN eliminates the risk of overcorrection or development of asymmetry, as happens with botulinum toxin injections, since the doctor sees changes from procedure to procedure and can, in agreement with the patient, reduce the course if the desired rejuvenation effect has already been achieved.

EJI ARGIRELIN is injected directly into the skin using a micropapular technique, however, the cosmetologist can diversify the technique of administering the drug – it is possible to use a moso- and dermaroller, iontophoresis, electroporation, which is very useful when working with patients who avoid the "classic" injection.

EJI ARGIRELIN treatment results in a 37% reduction in wrinkle depth in 28 days. Other effects include the following:

  • "tired" the face takes on a cheerful and fresh look,
  • hypermimicry is eliminated,
  • the skin does not deform and does not form creases.

It should be remembered that EJI ARGIRELIN works with mimic wrinkles, while to restore the structure of the skin frame, it is necessary to use remodeling peptides as part of SAKURA, EJI, EXTRA. These drugs, together with ARGIRELIN, can be purchased at the distribution company I-Сosmetolog, which is the official representative of Japan Cosmetics in Ukraine.

EJI ARGIRELIN can work not only as a replacement therapy, but also in combination: for example, it perfectly prolongs the action of botulinum toxin preparations and can be used both in a complementary and supportive role. EJI ARGIRELIN injections in combination with botulinum therapy is a fairly safe method of prolonging the therapeutic effect, which will help reduce the number of injected botulinum units in the future, as well as avoid resistance to them.

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