The possibilities of hyaluronic acid are far from being exhausted by moisturizing the skin. One of its important properties from the point of view of a beautician – this is the ability to influence inflammatory responses, including accelerating healing in controlled inflammation caused by the introduction of fillers. In the skin, hyaluronate is actively involved in hemostasis, re-epithelialization, as well as in the processes of dermal remodeling. Clinical studies of innovative products of the ART FILLER® line; from FILORGA demonstrated the ability of hyaluronic acid to influence the synthesis of collagen, which means prolonging the youthfulness of the skin. Read more about this at estet-portal.com.
Scientific confirmation of the effect of hyaluronic acid on collagen synthesis in the skin
Scientific studies have shown that intradermal administration of high molecular weight hyaluronic acid using a mesotherapy technique can stimulate the proliferation of fibroblast growth factor in the skin. Using various chemical and histological methods, scientists have found that hyaluronate stimulates the proliferation of fibroblasts, as well as vascular endothelium, epithelial cells. the organization conducting the assessment in the "blind" research – GREDESCO.
Multicenter Blind randomized comparative clinical trial was conducted for 18 months. The aim of the study was to evaluate the efficacy and safety of ART FILLER®. The assessment was made using the LEMPERLE Rating Scale (LRS) and the GAIS Overall Aesthetic Improvement Scale by instrumental measurements (profilometry and high-frequency skin ultrasound). "Blind" assessed by an independent GREDECO center and study subjects from day 0 (D0) to the end of 6 months
Inclusion Criteria:
• Fitzpatrick skin types – I – IV• LEMPERLE rating scale: "crow's feet" - 2 points, nasolabial folds – from 3 to 4 points.Among the individuals who participated in the clinical study, 90% were women and 10% were men.
Clinical results: correction over 18 months
Illustrations of assessment of overall improvement with profilometry
Products of the ART FILLER® belong to class III medical devices. They are manufactured by FILORGA Manufacturing and bear the EU CE marking (CE 123).
FILORGA's ART FILLER products restore the skin structure deformed due to the aging process: fill and smooth wrinkles, restore volume.
• ART FILLER® UNIVERSAL is an injectable implant designed to fill medium to deep skin folds when inserted into the mid or deep dermis, as well as to add volume and contour to the lips.• ART FILLER® VOLUME is an injectable implant designed to restore facial volume when injected subcutaneously, supraperiosteally, or by injection into the deep dermis.
• ART FILLER® FINE LINES is an injectable implant designed to fill fine wrinkles and small skin folds (crow's feet and nasolabial folds) when inserted into the superficial dermis.• ART FILLER® LIPS is an injectable implant designed to increase the volume and/or shape of the lips, as well as to smooth out medium to deep skin imperfections.
The filling process may require re-correction to achieve the desired result.
The physician should advise the patient of possible unwanted side effects of implantation of the product, which may appear immediately or occur later. These side effects include:
• inflammatory reactions (redness, swelling, erythema),
• itching, pain when touching the injection site.
These reactions can last for about a week. These potential risks must be taken into account. The patient should immediately inform the doctor if the inflammatory reaction does not go away for more than 1 week, or if any other side effects occur.
Thus, as a result of the administration of ART FILLER® preparations; from
achieves the effect of volume correction and comprehensive treatment and preventive care that slows down skin aging, which has been proven by independent clinical and instrumental studies.
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