What Substances Cause Coffee Addiction?

     It is already difficult for each of us to imagine our day without mentioning coffee. We hear the word when we talk to people, we see numerous cafeterias on our way to work, and most of us drink coffee several times a day. Until now, there is no unambiguous correct opinion whether coffee is useful or harmful. This question worries both patients and doctors. On this basis, researchers do not stop learning more and more about coffee. What do we still not know about coffee? Read on estet-portal.com

What  Substances that cause addiction to coffee?

    Coffee is one of the most popular drinks that millions of people around the world drink every day. For many years there have been discussions about the dangers and benefits of this drink. Some studies claim that the benefits of coffee predominate, others say otherwise. Bad coffee or not, but the fact that some people just "can't get through the day" without coffee - really exists. Probably everyone has heard the phrase "drank coffee - woke up" or “I’m going to go get some coffee, it’s so bad, I can’t do anything.” Many attribute this to habit or addiction to caffeine. But scientists have found that there are people who are simply not able to function without a few cups of strong coffee a day. Why is this happening?

     Coffee contains 1,200 chemicals, of which almost 800 determine its taste. In dependence on coffee "pull" alkaloids theophylline and theobromine. It is without these substances that a person “cannot live.”

The reason for addiction to coffee is in the genes

     Suspicions about differences in genes between people who drink and those who do not drink coffee have long existed. In the course of research, it turned out that variations in the two genes AHR and CYP1A2 allow their carriers to absorb coffee better than others. The study identified 6 more "coffee genes."

     More than 120,000 coffee drinkers have been deciphered. As a result, 6 new regions of the genome were identified. Small point mutations in them are responsible for the effect that caffeine has on health. Two of these genes are responsible for the rate of caffeine metabolism. The next two are responsible for the degree of pleasure when drinking coffee. The remaining two genes are responsible for lipid and glucose metabolism, which are associated with the metabolism and neurological effects of caffeine. With all this, mutations in genes that are associated with high coffee consumption are also responsible for addiction to smoking and a tendency to obesity and diabetes.

     This supports the fact that coffee addiction is the result of natural molecular mechanisms in some people. The use of individual doses of caffeine is regulated by the body's ability to metabolize caffeine. At the same time, in coffee lovers, this metabolic rate is very high, and it does not harm the body. Therefore, coffee lovers can comfortably enjoy a few cups of coffee a day and not experience discomfort or insomnia.

Benefits of caffeine

    Many studies have proven that caffeine – it is a storehouse of antioxidants, it also has a positive effect on cognitive function and has an anti-inflammatory effect. Caffeine is considered a mild antidepressant. At the same time, coffee has the ability to raise blood pressure and suppress insulin activity, making it undesirable for people prone to hypertension or diabetes.

Is coffee healthy? Benefits of frequent coffee drinking:

• Caffeine prevents the development of compounds of excessive phosphorylation of tau-proteins. The presence of these proteins causes Alzheimer's disease.
• Coffee protects against a rare disease - primary sclerosing cholangitis. Moreover, regular consumption of the drink prevents the development of liver cancer and cirrhosis.
• Each cup of coffee reduces the risk of developing endometrial cancer by about 7%, because coffee reduces the level of estrogen and insulin in the blood, and these hormones contribute to the development of oncological processes in the endometrium. Therefore, obesity associated with elevated estrogen levels increases the risk of endometrial cancer.
• Consumption of caffeine has been found to reduce a person's risk of suicidal thoughts. After all, caffeine stimulates the central nervous system and is a mild antidepressant. It enhances the release of the neurotransmitters norepinephrine, serotonin and dopamine.

Like many foods, coffee also has a negative impact. It all depends on how many cups of coffee you drink a day.

Negative sides  regular  coffee consumption:

• Among the number of cases of sudden death, almost 70% of people turned out to be coffee drinkers. There is no explanation for this yet.
• When drinking coffee during pregnancy, caffeine negatively affects the fetus. Studies have shown that when a pregnant woman consumes 100 mg of caffeine per day from sources of caffeine such as coffee, tea, energy drinks, chocolate, desserts and cocoa cakes, fetal weight at birth is reduced by 20 g, and the duration of labor is increased by 5 hours. At the same time, every 100 mg of pure caffeine lengthens the gestation period by 8 hours.

   Therefore, during pregnancy, it is worth limiting the consumption of tea, coffee, chocolate. And it's better to give up these products for a while.

    Thus, coffee has a number of both positive and negative effects on the body. In any case, people who are found to be addicted to coffee at the gene level should not refuse it. The main thing is to know the measure in everything. And then your body will not feel harm from coffee. And do not be surprised why some people feel bad without coffee - these are normal phenomena, which is proven at the gene level.