The Many Faces of Janus: Connective Tissue Dysplasia Syndrome

According to modern concepts, connective tissue dysplasia syndrome can manifest for the first time not only in childhood, but also at a more mature age.

Patients with connective tissue dysplasia syndrome, unaware of its presence, often seek aesthetic correction from specialists working in the beauty industry.

Unfortunately, connective tissue dysplasia syndrome often goes unnoticed not only by patients, but also by doctors themselves. Meanwhile, patients with this pathology require a special and differentiated approach to treatment.

Exclusively for estet-portal.com Maria Shirshakova, Candidate of Medical Sciences, international expert on injectable rejuvenation techniques, spoke about the relevance of connective tissue dysplasia syndrome for specialists working in the field of aesthetic medicine.

Connective tissue dysplasia syndrome: how relevant is it

The fact is that connective tissue dysplasia syndrome – this is a completely new topic in cosmetology, but not a completely new topic for general medicine.

Aesthetic medicine steps on the path of evidence-based medicine. We stop doing "handicraft" and we begin to integrate the latest scientific data into the practical life of cosmetologists.

Currently, a sufficient pool of patients with various adverse events after injection contouring, in particular, the use of drugs based on hyaluronic acid, has been accumulated.

It became clear that the indications for various drugs are identical, and the variety of patients – great.

Therefore, the goal of creating selection criteria for different methods, prescribing certain drugs based on hyaluronic acid or other fillers is to minimize complications, improve the quality of life of patients and optimize therapy.

Ehlers-Danlos Syndrome. Dangers of the vascular type of the syndrome

What are the causes of the development of connective tissue dysplasia syndrome

We know that the syndrome of connective tissue dysplasia is diverse and many-sided, like the many-sided Janus.

There are rare hereditary systemic diseases of the connective tissue such as Ehlers-Danlos syndrome, Morfan syndrome, which most specialists know about.

At the same time, an undifferentiated form of connective tissue dysplasia syndrome occurs daily in the practice of specialists working in the field of aesthetic medicine.

According to the statistics of our clinic, every fourth patient who applies for cosmetic correction has signs of a violation of the embryonic development of the connective tissue.

Connective tissue dysplasia syndrome can manifest itself as the formation of thin and atonic skin, or vice versa – in the form of skin hyperextensibility, striae, as well as various bone deformities, joint hypermobility.

By screening for connective tissue dysplasia syndrome, we can differentiate these patients and apply appropriate treatment protocols.

The importance of timely diagnosis of connective tissue dysplasia syndrome

A large experience has been accumulated in the management of patients who develop irreversible facial deformities, persistent chronic edema, and mallar edema over the course of several years.

We have concluded that there is a certain phenotype of patients that needs further investigation.

This is how the idea of integrating the concepts that exist today in hematology, pediatrics, and embryology into the field of aesthetic medicine was born.

Skin lesions in connective tissue diseases

As a result, protocol for primary screening of patients who have certain phenotypic signs of connective tissue dysplasia syndrome.

A doctor right at the appointment may suspect that the patient has a violation of the embryonic development of the connective tissue.

Afterward, the patient must undergo laboratory screening, the purpose of which is to determine the presence of increased connective tissue catabolism. At the same time, such studies can be carried out even in an ordinary clinic.

In addition, according to recent studies, patients with connective tissue dysplasia syndrome have a premature aging tendency.

Therefore, the sooner such patients are identified - and I remind you that this is every fourth patient who visits the clinic of aesthetic medicine - the better their life will be in the future.

Thank you for staying with estet-portal.com. Read other interesting articles in the "Experts" section. You may also be interested in: Connective tissue dysplasia can occur in aggravated pregnancy