The age of women after 40 is not in vain called delicate: during this period, the first symptoms of hormonal changes in the body associated with the approach of menopause often appear, the manifestations of skin aging associated with exposure to both negative environmental factors and own aging processes. Today, cosmetologists have many tools at their disposal to help the patient reduce the manifestations of involutional skin changes and give the face a young, healthy look as much as possible. One of the most frequent recommendations is – intensive injection therapy with Meso-Wharton P199™. Read more about the fundamentally important features and mechanisms of action of the drug in our material.

What mechanisms hinder the preservation of youthful skin

Aging – This is a natural natural process in the human body, which consists in a progressive decrease in the functions and capabilities of organs and systems, including skin cells. Aging is caused by the genetic program, as well as adverse environmental factors, especially smoking and insolation.

Young skin contains the optimal quantity and quality of the main cells of the dermis - fibroblasts, which synthesize collagen and elastin fibers, as well as the main component of the extracellular matrix – hyaluronic acid.

Unfortunately, with age, the quality and quantity of actively working fibroblasts decreases, since they have a limited number of divisions – mitoses, also in the process of cell life under the influence of negative factors, errors accumulate in the DNA structure, which can persist from division to division and affect the quality of the produced extracellular matrix. It is these processes that manifest themselves in the form of violations of the structure of the dermis, which is externally accompanied by the following signs:

  • poor healing of skin wounds;
  • thin, dry skin with fine wrinkles;
  • loss of elasticity and turgor;
  • an increase in skin area, the appearance of large wrinkles and creases.

Unfortunately, even the most high-quality and expensive care is not able to radically affect the aging process and preserve youth for many years.

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The key features of Meso-Wharton P199™ for youthful skin

On the cosmetic market, there are many drugs and techniques aimed at stimulating the cells of the dermis – fibroblasts – in order to potentiate the production of its own hyaluronic acid, collagen and elastin fibers. But such an approach turns out to be not very effective over time, since fibroblasts exhaust their ability to divide with age and, despite their stimulation, the expected effect does not occur. In this case, tissue-specific stem cells, which in the process of division and differentiation turn into "young" cells, are an effective resource for cellular renewal of the skin. fibroblasts. The action of Meso-Wharton P199™ injectable, represented by Emet™, aims to increase the amount of « young» active fibroblasts capable of restoring the intercellular matrix due to the synthesis of new collagen, elastin, glycosaminoglycans. This effect is achieved by stimulating the activity of the skin's own mesenchymal stem cells, which restores the physiological regeneration of the skin lost over time. and "returns" youth in a natural way.

The fundamental difference in the correction of involutional skin changes with Meso-Wharton P199™ consists in activating the proliferation and differentiation of the skin's own stem cells into young functional cells (fibroblasts and keratinocytes)

The mechanism of operation of the drug, administered by injection, consists in the following intradermal processes:

  • creates optimal conditions for migration, proliferation and differentiation of skin's own tissue-specific stem cells;
  • replaces sluggishly renewed cellular structures;
  • restores the physiological regulation of cell activity.

Activation of one's own tissue-specific stem cells becomes possible due to the content of the unique patented component – synthetic polypeptide Wharton Jelly Peptide P199™, which has a scientifically proven targeted effect on the own stem cells of the epidermis and dermis. The preparation also contains hyaluronic acid, growth factors, vitamins and microelements, coenzymes and nucleic acids – everything you need to restore youthful skin at the molecular level.

Youthful skin effects achieved with Meso-Wharton P199™

kak-vernut-molodost-kozhi-printsipialno-vazhnye-osobennosti-meso-wharton-p199The most important effect that a woman expects from the procedure – This is a visible improvement in the quality of the skin and a decrease in the appearance of age-related signs. Injections of the medicinal product Meso-Wharton P199TM can even give the patient a little more than she expects:

  • skin will be visibly hydrated and smoothed;
  • the effect of lifting on the face will be noticeable;
  • superficial wrinkles will become almost invisible;
  • deep wrinkles will become less pronounced;
  • the complexion will even out, the skin will noticeably freshen up.

The number of necessary procedures in the course of treatment is determined by the doctor based on the characteristics of the skin of a particular patient, as a rule, this is at least 4 procedures with a frequency of once every two weeks. A woman should be warned that the result of treatments with Meso-Wharton P199TM is cumulative, and the effects will not be observed immediately, but as skin cells divide and differentiate. However, the gradual renewal of the cell pool of all layers of the skin, the increase in the activity of its cells, the strengthening of the barrier properties will allow maintaining a stable result for a long time, and one maintenance course of injections per year will be quite enough to preserve youthfulness of the skin.

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