Rosacea on the face can be successfully corrected: the possibilities of Mezoxanthin

Rosacea on the face – a chronic relapsing disease of a polyetiological nature and characterized by a staged course, accompanied by redness, expansion of small and superficial vessels of the facial skin, the formation of papules, pustules and edema. Patients with rosacea make up about 10% of all visits to a dermatologist, dermatosis usually begins at the age of 30-40, reaches its peak between 40-50 years, women are more often ill.  At the initial stages, rosacea responds well to therapy, and many cosmetologists choose Meso-Xanthin F199^ТМ for this. What is its effectiveness in rosacea, and what effect can be expected from it, considered estet-portal.com.

What factors regarding facial rosacea should be considered in therapy

The pathophysiological mechanisms of the onset and development of rosacea are still the subject of scientific debate. Numerous studies show the involvement of a large number of

• immune cells
• blood cells
• protease
• inflammatory mediators,
• antimicrobial peptides, leading sequentially to hypervascularization, inflammation and hyperplasia of the connective tissue and sebaceous glands. The provoking factors for the development of the disease may be innate susceptibility to harmful environmental factors, diseases of the gastrointestinal tract, endocrine disorders, and the role of the tick is also high Demodex folliculorum. According to new trends in the coverage of pathogenesis, the leading role is determined by the reactions of the innate immunity of the skin with an increased content of cathecilidine. All of the above factors lead to the development of chronic inflammation, dysregulation of neurovascular connections in the skin and neoangiogenesis, and damage to the architecture of the intercellular matrix. Clinically, persistent erythema is formed, against its background of telangiectasia, papules and pustules are formed, and in severe stages & nbsp; – phymatous changes are formed.

The pathogenesis of rosacea on the face has not yet been fully explored, but the causes of the onset of the disease are most often the use of spicy, hot food, strong alcohol, exposure to strong dry winds, and sudden changes in temperature from heat to cold

The choice of therapy for each patient is made individually, taking into account the factors that provoked rosacea on the face, skin type and the degree of neglect of the disease, the presence of concomitant diseases. Many cosmetologists choose Meso-Xanthin F199^ТМ (Mezoxanthin), presented on our market by by EMET^TM.

as the basis for the treatment of rosacea manifestations.

The benefits of Meso-Xanthin F199^TM in the treatment of rosacea

If a patient with rosacea  asked for help in that phase of the disease, when the skin is abundantly affected by papules and pustules, a specific & nbsp; therapy with a dermatologist. Therapy with Mezoxanthin is relevant for episodic erythema or persistent erythematous-telaegiectatic stage.

Mezoxanthin is becoming the drug of choice for many cosmetologists dealing with rosacea, as this injectable medicinal product contains substances that have anti-inflammatory effects, epigenetically regulates collagen production and has high antioxidant activity.

The main active substance of Mezoxanthin is the unique carotenoid F199 Fucoxanthin, which, when injected into the skin  inhibits inflammation by suppressing the expression of COX2 mRNA, is able to affect the metabolic activity of neutrophils, reducing cell infiltration. In addition, Fucoxanthin blocks endothelin receptors, reducing the manifestations of vasodilation, and restoring the normal process of collagen formation, & nbsp; prevents passive filling of vessels with blood and, as a result, their expansion. By using Mezoxanthin in the first stages of the disease, it is possible to reduce clinical manifestations and prevent further progression to more severe stages.  Among other important components of Mezoxanthin, which are needed in the treatment of rosacea, we draw attention to the following:

• copper peptide – reduces inflammation and enhances microcirculation;
• vitamin C – strengthens capillary walls and improves blood flow;
• vitamin E – protects cell membranes from destruction by free radicals;
• growth factors (epidermal, insulin-like) – stimulate metabolic processes in cells, trigger neocollagenesis, improve skin texture;
• hyaluronic acid – has anti-inflammatory properties, restores water balance in the skin.

The active substances contained in the Mezoxanthin preparation significantly reduce erythema, the severity of the vascular pattern in rosacea, improve skin elasticity, tone and color.

Mesoxanthin may be used in patients 18 years of age or older when indicated. This advantage of the drug makes it possible to include it in the complex therapy of rosacea in the early stages of the disease and quickly achieve success. Patients note that after a course of procedures, the number of which is determined by the doctor, there is less redness, the complexion and skin texture improve, itching and other unpleasant sensations go away, the face looks completely healthy.