Symptomatic treatment of rosacea with botulinum toxin

The problem of correction and prevention scars of various origins has been and will continue to be relevant due to the wide spread of pathology and the complexity of therapy. The same applies to such chronic multifactorial dermatosis as rosacea. Indications for the use of  Botulinum toxin type A in medicine are growing daily. Therapy of pathological scars and symptomatic treatment of rosacea with the use of neurotoxin slowly, but surely, take their positions among them, showing good results. Read on estet-portal.com how botulinum therapy can affect 

• Botulinum toxin as a method of scar prevention and correction
• Symptomatic treatment of rosacea with using botulinum toxin
Botulinum toxin as a method of prevention and correction of scars

Botulinum toxin inhibits fibroblast proliferation and therefore collagen production. According to animal studies, under the influence of neurotoxin also decreases the amount of connective tissue growth factorand transforming growth factor-.beta;1. Follow us on 

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! Botulinum toxin type Apreparations 

 are 

local muscle relaxants with long-term action, which allows them to be used for pathogenetic prevention of scar formation. Injection of neurotoxin into the subcutaneous muscles leads to prolonged muscle relaxation, due to which the skin will not stretch during facial movements. In this case, botulinum therapy excludes excessive tissue stretching, which exacerbates inflammation and stimulates intensive collagen production, even at the stage of scar formation, as an unfavorable risk factor for its development.

This method should be used 

after excision of an existing scar 

to improve the cosmetic result.

Read also: 

Anatomy of botulinum therapy: aesthetic correction of the lower third of the face

The use of botulinum therapy for existing  hypertrophic and keloid scars

 will reduce pain and sensitivity in the scar area, releasing the nerve fibers woven into the scars.

In this case, it is recommended to injections of botulinum toxin

 directly into the scar tissue. According to some studies, this will also help to change the consistency of hypertrophic scars to a softer one and reduce erythema.

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! In the presence of hypotrophic and atrophic

 scars, botulinum toxin is injected into the scar area, which leads to a smoothing of the skin surface and 

reduction of the scar visualization due to the relaxation of the subcutaneous muscles. Botulinum toxin reduces inflammation in the scar area and improves wound healing by inhibiting the release of pro-inflammatory neurotransmitters,

 such as substance P and calcitonin gene-related peptide, which will ultimately lead to less pronounced scar

. According to clinical studies on the basis of the Mayo Clinic (USA), the introduction of a neurotoxin 

into the area of ​​the emerging scar on the face

 leads to the subsequent formation of  normotrophic scar. Symptomatic treatment of rosacea with botulinum toxin Analyzing the data of the conducted studies, it becomes clear that injections of botulinum toxin can 

positively influence the course of 

rosacea. The mechanism is not 100% understood, but the good results can be explained by the wide interaction of the structures of the skin and the nervous system: The neurotoxin blocks the release of the neurotransmitter acetylcholine in the peripheral autonomic nerve fibers of the vasodilator system of the skin, thereby preventing vasodilation, reducing hyperemia. As already known, 

botulinum toxin type A

 inhibits the release of neuropeptides such as 

substance P

 and calcitonin gene-related peptide. Substance P is involved in the release of inflammatory mediators and activation of pain receptors, increases the permeability of the vascular wall.  

release of inflammatory mediators

 and dilation of cranial vessels.

Read also: Modern aspects of diagnosis and treatment of rosacea

Influencing all these factors can lead to  reduction of local inflammation and skin flushing in rosacea, while relieving pain.

Research on the effect of botulinum toxin on the course of rosacea and the condition of pathological skin scars is ongoing, but already at this stage it can be understood that the use of neurotoxin safely and effectively reduces local inflammation and hyperemia of the skin, acting on neurotransmitters.

Read also: Algorithm for rehabilitation of patients after rosacea treatment

Due to  prolonged effect of muscle relaxation and reduction of skin tension in the area of ​​damage, botulinum toxin contributes to the formation 

normotrophic

 scar, improvement of the clinical picture of existing hypertrophic and atrophic scars, reduction pain in the presence of keloids. More interesting stuff on our YouTube channel

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