All living cells communicate with each other and with their environment, and skin cells are no exception. Therefore, we are interested in the processes that take place between skin cells, how they are carried out normally, how they are transformed with age, and whether we can influence these changes with a therapeutic purpose. Today, our ability to heal aging, photodamaged skin to improve its appearance is based on the results of scientific research and involves the use of pharmaceuticals that improve intercellular communication.
Information exchange between cells: the role of gap junctions
Cytologists were actively engaged in the study of the issue of intercellular communication in the 60-70s of the last century. The experiments carried out unequivocally showed that neighboring cells exchange various molecules in places of close physical contact.
Microscopic studies indicate the formation of extended sections within the plasma membranes of two neighboring cells, approaching at a distance of several nanometers. In this case, a single system is formed, which today is called a gap-like contact or nexus. This narrow gap – not an empty place, but a special structure that connects the cytoplasm of cells with each other.
Further biochemical studies have shown that each channel consists of protein molecules of the same family. In the late 1980s, they were identified as conexins (Cx). Six conexin molecules form a semi-channel in the outer side of the cell membrane of one cell, six – other.
Two such complexes of neighboring cells are connected into a single system (end to end), forming an extended channel for intercellular information exchange. Gap contact area – this is a grandiose association (up to 120 thousand molecules) of conexins into a single complex consisting of thousands of channels.
At the same time, the nexus area is constantly transforming, updating in composition or extent. Changes clearly coordinate the relationships between neighboring cells.
What are the consequences of gap junction failures
In the human body, gap junction disorders can lead to a wide variety of pathologies from hearing loss to cardiovascular disease, skin problems, and some forms of cancer.
The human genome contains genes encoding 24 types of conexins, the most common of them – Cx43. Skin cells synthesize up to nine types of these protein molecules. The exchange of signals in the form of ions, small metabolites, secondary messengers at the level of gap junctions establishes communication channels between skin cells, forms communication channels, as between nearby keratinocytes – and adjusts the relationship of the epidermis and the dermis as a whole. Intercellular interactions through gap junctions (GJIC) – the key to growth and differentiation, to the maintenance of homeostasis and morphogenesis.
Intercellular interactions through gap junctions (GJIC) – the key to growth and differentiation, to the maintenance of homeostasis and morphogenesis.
How to improve intercellular communication: the possibilities of peptides and exopolysaccharides pHformula
Today, our ability to heal aging, photo-damaged skin to improve its appearance is associated with the use of pharmaceutical preparations such as pHformula POINT creams that can regulate communication interactions. These are biotechnological artificial peptides and exopolysaccharides of the halophilic bacterium Halomas eurihalina. These substances with the patented name C2C (Cell to Cell) Messenger are included in pHformula – Vita C, Hydra, Power Essenes Tonic.
VITA C Concentrated Corrective Serum
Excellent product for skin health. It draws its power from a combination of various forms of vitamin C, combined with a unique cell-to-cell communication system, enhancing skin lightening to a higher level.
KEY ACTIVE COMPONENTS
- Vitamin C Complex (encapsulated sodium ascorbyl phosphate, stabilized vitamin C, bitter orange extract);
- C2C Messenger intercellular communication complex;
- hyaluronic acid complex (hyaluronic acid, glycosaminoglycans, ginkgo biloba leaf extract, jojoba oil);
- 3D Hydra Moisturizing Complex (natural moisturizing factor).
BENEFITS
- improves skin tone and texture;
- gives skin a more youthful appearance;
- reduces wrinkles and expression lines.
For all skin types.
HYDRA Concentrated Corrective Serum
Contains a special blend of active ingredients and moisture-binding ingredients that intensely hydrate the deepest superficial layers of the skin.
KEY ACTIVE COMPONENTS
- ferulic acid complex (ferulic acid, vitamin E);
- C2C Messenger intercellular communication complex;
- hyaluronic acid complex;
- 3D Hydra Moisturizing Complex.
BENEFITS
- provides an optimal level of moisture retention in skin cells;
- immediate skin hydration and protection;
- Shine enhancement.
For all skin types.
Power Essenes Tonic Serum Spray
Contains powerful ingredients that leave skin feeling plump, hydrated and refreshed. The natural ingredients in this pHformula product deliver moisture and nutrients to the skin to improve texture and radiance. The product absorbs quickly and prepares the skin to better absorb additional products such as serums while protecting the skin throughout the day.
KEY ACTIVE COMPONENTS
- 3D Hydra complex;
- Brightening Complex (Watercress Extract, Vitamin B3, ECB Factor)
- anti-aging complex (Palmitoyl Tripeptide-5, watermelon extract, Nannochloropsis oculata algae extract, superoxide dismutase (SOD));
- protective complex (marine proteobacteria extract, fermented yeast, witch hazel extract).
BENEFITS
- protects the skin from moisture loss;
- rejuvenates and delays premature aging;
- brightens skin, evens out skin tone;
- protects the skin from environmental influences;
- moisturizes well.
For all skin types.
Thus, pHformula Vita C, Hydra and Power Essenes Tonic serums contain patented substances that can regulate the process of intercellular communication and, as a result, improve the texture, quality and appearance of the skin.
To get comprehensive information about the features of the use of pHformula products, as well as to purchase the drugs you are interested in, please contact the official representative of the brand in Ukraine – company "Cosmetic Group".
Share:
Add a comment