Age-related skin changes are caused by three main processes – this is a violation of cellular metabolism, activation of the damaging effect of free radicals, increased dehydration. To slow down the aging process, redermalization procedures with Hyalual preparations are successfully used, the components of which affect all three processes that provoke age-related changes: succinate is responsible for the antioxidant effect and restoration of metabolic processes in cells, and for moisturizing – hyaluronic acid.
How these active components of redermalization work was reviewed by estet-portal.com.
The role of succinate in cell metabolism
Cell metabolism is of interest to a cosmetologist from the point of view of the work of the main cells of the dermis – fibroblasts. If they are active and produce collagen, elastin, the skin retains its youthful firmness and elasticity.
The activity of fibroblasts, as well as any cells of a living organism, depends on the state of mitochondria – special cellular formations, the main function of which is to generate energy. Various complex processes in the body associated with age-related changes are also reflected in the state of cellular mitochondria. They slow down the production of energy, which means the inhibition of all metabolic processes, which leads to inevitable aging.
• The first stage of the path leading to the production of the necessary energy for the cell is the breakdown of fats, carbohydrates and proteins that have entered the body with food. The end products of this breakdown are carboxylic acids, which enter the central part of the mitochondria
• The next energy stage takes place directly in the cellular mitochondria, where carboxylic acids enter into a cyclic biochemical process known as the Krebs cycle.
The German chemist Hans Krebs, who discovered this cycle of transformations, was awarded the Nobel Prize.
Approximate essence of the Krebs cycle consists in the fact that with the participation of oxygen, 8 chemical reactions occur cyclically, in the process adenosine triphosphoric acid (ATP) is formed.
Without which the permeability of cell membranes for oxygen and nutrients will be disrupted, all vital processes in the body will stop.
In the process of chemical transformations of the Krebs cycle during the 5th reaction, succinate is produced, which immediately becomes a substrate for starting the 6th reaction. The ATP produced in the mitochondria enters the cytoplasm of the fibroblast and gives energy to all the processes for which these dermal cells are responsible.
Influence of the redermalization procedure on the activation of cell metabolism
When many processes slow down in the body with age, this is reflected in the work of the cellular mitochondria of the skin. A manifestation of such aging processes is a decrease in the activity of fibroblasts, which leads to skin dehydration, deterioration in the production of collagen and elastin, which means – and to the manifestation of external signs of age-related changes.
With the help of the redermalization procedure, it is possible to activate fibroblasts due to the fact that Hyalual preparations contain the necessary component of the Krebs cycle – succinate. Getting into the dermal cells, this substance affects the functioning of mitochondria and enhances the synthesis of energy necessary for skin regeneration.
We should not forget about the antioxidant properties of succinate. Once in the dermis, the substance actively blocks free radicals, preventing their destructive effect on & nbsp; cells, and also stimulates the proliferation of fibroblasts.
The considered processes with the participation of succinate make it possible to fully understand the importance of this substance for slowing down the processes of cellular aging and improving metabolism, which means – and the value of the redermalization procedure with preparations Hyalual, which contain succinate.
The article was written according to the recommendations of the Hyalual company. As a reminder, you can purchase the original products of the company only from the official distributor.
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