How to rejuvenate the eye area: MesoEyeTM C71 and its possibilities

According to the observations of psychologists, we determine the age of a person, unconsciously evaluating his area around the eyes – skin condition, the presence or absence of wrinkles, hernias, edema and other aesthetic problems that are usually associated with the aging process. Experts note that the severity of deformities in the periorbital region does not always depend directly on age, they are affected by the state of the microvasculature in the tissues of the eyelids. About how you can correct the aesthetic problems of this area, and due to which the drug MesoEye^TM C71 from the company Emet ™ shows high efficiency in such a correction, considered estet-portal.com.

Why aesthetic problems form in the periorbital zone

The condition of the periorbital region, more than any other area of ​​the face, depends on aggressive external influences, since it is formed by thin and very sensitive, constantly functioning structures. Here, the skin is practically devoid of sebaceous glands and a layer of subcutaneous fat, while the periorbital zone is tightly braided with a network of arterial, venous, and lymphatic vessels located close to the surface of the skin and representing a single microcirculation system. In addition, this area experiences constant muscle tension due to facial expressions.

The severity of atrophic processes and the state of the microvasculature in the tissues of the upper and lower eyelids are the main link in ensuring metabolic processes and the fundamental mechanism in the pathogenesis of the formation of periorbital "hernias"; and furrows, wrinkles and folds of the skin, «dark circles» and edema.

The first reason for the formation of aesthetic problems in the area around the eyes is the deterioration of the microcirculatory bed, namely the development of vasospasm and an increase in the permeability of the vascular wall in the tissues of the eyelids

The state of the vascular system of the periorbital region is largely determined by the level of expression of genes encoding chemokines and other signaling molecules in endothelial cells of arterial, venous and lymphatic vessels. These signaling molecules increase the permeability of the vascular walls, provoke vascular spasms and dilations, and impair lymph flow, so it is important to find a way to influence the expression of genes that regulate their activity. The MesoEye^TM C71 injectable preparation was created taking into account the maximum of pathogenetic mechanisms & nbsp; violations of microcirculation in the periorbital region.

Peculiarities of MesoEye^TM C71 in the correction of the periorbital zone

MesoEye^TM C71 prevents the increase in the permeability of the walls of blood vessels and spasm of the arteries under the action of the cytokines interleukin 1α (IL1A) and tumor necrosis factor (TNF), as well as inflammatory chemokines CXCL1, CXCL8 and CCL21, inhibiting the expression of the corresponding genes and stimulating the expression of the CXCL12 chemokine gene (stromal cell derived factor 1α/SDF1α), which stabilizes the endothelium of blood vessels. MesoEye^TM C71 contributes to a more effective and faster resolution of conditions caused by impaired vascular permeability by stimulating the activity of the signaling pathways VEGFC-VEGFR3, ANGPT1-TIE2 and IL7-IL7Rα-IL2RG, directly improving the drainage function of the lymphatic vessels and preventing enlargement vascular permeability, diapedesis and the occurrence of local edema. The detected effects of the drug lead to stable stabilization of the vascular endothelium of the three systems – arterial, venous and lymphatic.

MesoEye^TM C71 is designed to meet the maximum pathogenic mechanisms  microcirculation disorders in the periorbital region

The activity of MesoEyeTM C71  is based on the main components it contains:

• Hexapeptide-17 - acts on the δ-opioid receptors of the lymphatic vessels. Due to this effect, the walls and valves of these vessels begin to actively move, directing the lymph to the exit from the stagnant area; the vessels of the venous system cease to expand pathologically and their permeability decreases; there are more arterial vessels, the volume of blood flow in them is higher
• PeriOrbital Reptide XP2 – inhibits angiotensin-converting enzyme, thereby relieving spasms of arterial vessels in the area around the eyes, and also slows down pathological glycation of collagen fibers.

Thus MesoEye^TM C71 from Emet ™   allows you to solve the main aesthetic problems of the periorbital zone, with which patients usually go to the doctor, dreaming of rejuvenating the area around the eyes. Correction is carried out quickly, safely for the patient and with long-term preservation of the result. The drug can be used both as an independent injection procedure and in complex rejuvenation – combined with botulinum therapy, contour plastics, hardware techniques.