Decrease in dermal collagen and elastin contributes to the age-related decrease in skin volume and a violation of its quality. To effectively combat age-related changes in the face, it is recommended to restore the volume of tissues lost under the influence of gravitational ptosis and other manifestations of aging. Patients prefer face remodeling with the help of drugs that reliably have a high level of safety, do not cause discomfort during the procedures, and allow achieving the optimal result and maintaining it for a long time. Estet-portal.com offers to evaluate the unique principles of the action of the Radiesse drug, which has significant effects that allow you to defeat age-related skin changes.
The significant growth in the popularity of contouring over the past decades has led to the development of a number of new dermal fillers. Radiesse calcium hydroxyapatite injectable filler is one of the most promising and most studied soft tissue fillers.
Radiesse's triple action principle for a rejuvenating effect
Radiesse from Merz Aesthetics has a unique triple effect on facial tissue:
Restoration of volume and contours – allows you to safely, efficiently and easily to correct moderate and deep wrinkles.
Lifting – lifting and restoration of facial contour due to collagen-mediated volume replenishment.
Skin rejuvenation is a visible improvement in the quality of the skin of the face and body, which lasts for a long time.
Clinical studies have shown that Radiesse™ based on calcium hydroxyapatite, in addition to immediate volume replenishment, it can contribute to long-term improvement in skin condition as a result of collagen stimulation.
Neocollagenesis stimulated by Radiesse® is a very physiological two-step process where type 3 collagen is first synthesized and then type 1 collagen begins to rapidly increase after a few months.
Radiesse™ stimulates the synthesis of collagen and elastin dermal proteins, causes cell proliferation and neoangiogenesis much stronger than HA fillers. Stimulation of the formation of new capillary networks is especially important for the supply of the required amount of nutrients to the skin.
In addition to immediate wrinkle correction and volume replenishment, Radiesse™ promotes regeneration of skin structures, long-term improvement of its strength and elasticity.
Skin quality improvement in 4 main levels
Radiesse provides effective skin rejuvenation, improving its quality on 4 main levels:
- Activation of cell proliferation.
The administration of Radiesse stimulates the proliferation of skin cells. After the injection of calcium hydroxyapatite, a higher proliferation in the skin is observed compared with the injection of cross-linked hyaluronic acid.
- Increased collagen production. The introduction of calcium hydroxyapatite microspheres effectively stimulates neocollagenogenesis. After a single injection of Radiesse for 9 months, there is a marked thickening of the network of new type I collagen compared with the introduction of HA.
- Skin thickening. Already 3 months after a single injection of Radiesse, skin thickness increases by more than 50% compared to the original.
- Increased elastin synthesis. The introduction of Radiesse markedly increases the level of elastin in the skin. At 9 months after the introduction of Radiesse, there is a significant increase in the level of elastin, compared with HA.
Clinical studies have confirmed the ability of Radiesse to remodel the extracellular & nbsp; matrix and significantly more active stimulation of the production of collagen and elastin in comparison with preparations based on hyaluronic acid.
Numerous studies have proven the long-lasting effects of Radiesse. Instant lifting and volumizing effect Radiesse® gradually accompanied by the formation of new tissues through: neocolagenesis (production of type III collagen, gradually converted to type I), elastin production (improves skin elasticity), skin cell proliferation (fibroblasts), angiogenesis (formation of new blood vessels), which is especially important for the supply of the necessary amount of nutrients into the skin.
Result – long-lasting aesthetic effect characterized by an improvement in the quality of the skin, with increased density, elasticity and a healthy color.
Literature:
Yutskovskaya Y, et al. J Drugs Dermatol. 2014; 13(9): p1047-1052
Silver S.L., et al. Plast Reconstr Surg.2006; 118 (Suppl.3): 34S-45S
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