Injection rejuvenation is very popular among doctors and patients for several reasons: high efficiency, minimal recovery period, the ability to solve several aesthetic skin problems at once. The effectiveness, efficiency and safety of "beauty injections", among other things, largely depends on the quality, composition and, accordingly, the characteristics of the administered drug. Hyaluronic acid as a component of injectable preparations for skin rejuvenation has been successfully used for many years. However, only the Profhilo® bioremodeling procedure; thanks to the combination of high and low molecular weight HA, it provides high biocompatibility, reduced inflammation, instant results, prolonged effect and fewer injection points.
PROFHILO® bioremodeling agent; – 2 years on the Ukrainian market
Since PROFHILO® first appeared on the market (February 2015, Italy), more than 150 & nbsp; 000 procedures were successfully performed using it in 43 countries around the world. PROFHILO® twice awarded with international prestigious awards – AMEC 2015-2016 and Aesthetic Award 2016. This year, celebrating the 2nd anniversary of PROFHILO®; in Ukraine, we offer to remember what makes the product unique and get acquainted with the latest research on the use of the drug.
PROFHILO® –medical product for skin bioremodeling based on hyaluronic acid, produced by the largest private pharmaceutical company in Switzerland – Institute of Biochemistry SA (IBSA, since 1945).
PROFHILO® twice awarded with international prestigious awards – AMEC 2015-2016 and Aesthetic Award 2016.
Hyaluronic acid produced by IBSA – is an ultra-pure hyaluronic acid produced by a patented bio-fermentation process with Streptococcus Zooepidemicus bacteria, which is world-renowned as HIGH-GRADE for purity and safety.
At the heart of the PROFHILO® operating principle; – concept Hydrolift® action. It is an innovative approach to counteract the physiological depletion of hyaluronic acid in the skin, which restores hydration, elasticity and skin tone.
What's New: The unique characteristics of PROFHILO®; for bioremodelling
PROFHILO®, based on stabilized hybrid complexes of native hyaluronic acid, is the first product to use Nahyco Hybrid Technology, which is a unique and innovative thermal manufacturing process without the use of chemical stabilizers, patented by IBSA.
As a result, we have a product with unique characteristics:
- high HA concentration (64 mg/2 ml);
- highly controlled;
- extensive flow;
- low viscosity;
- does not contain exogenous residues of BDDE and other chemical stabilizers;
- low inflammatory response;
- thermally stabilized native HA is comparable in durability to gels based on chemically stabilized HA.
Mechanism of action of PROFHILO® for bioremodelling
Studies have shown that PROFHILO® improves the extracellular environment:
- provides favorable conditions for the recovery of fibroblasts, keratinocytes and adipocytes;
- promotes extracellular matrix remodeling, improves elasticity and support.
PROFHILO® SUPPORTS VIBRATION OF FIBROBLASTS
In vitro studies show elastin immunofluorescence in fibroblasts (human skin fibroblasts)
PROFHILO® SUPPORTS ADIPOCYTE VIABILITY
In in vitro studies, a red neutral oil was shown in adipocyte stem cells in adipogenic medium, 14 days after incubation.
PROFHILO® IN FABRICS:
- optimal ability to integrate into tissues;
- unique biophysical profile; in particular, the predominance of fluidity over elasticity (tan delta > 1), which is not shown in other cross-linked gels;
- distributes homogeneously in the fat cavities in difficult areas where even low viscosity fillers can create an uneven contour.
IBSA GPS scale based on current rheological data:
BIOREMODELING WITH PROFHILO®: INDICATIONS, TECHNIQUE, RESULTS
PROFHILO® designed for tissue remodeling and improvement of skin elasticity of the face, neck and body.
PROFHILO® affects:
- on the physiological process of tissue aging, in changes in elastin and collagen fibers;
- on the process of skin tissue repair in case of acne or scars;
- for cases of loss or reduction of subcutaneous fat.
Due to the unique rheological properties of PROFHILO®, the remodeling effect is easily achieved in just 2 sessions (4 weeks apart) using all possible aesthetic injection techniques in the deep layers of the skin.
Due to the unique rheological properties of PROFHILO®, the remodeling effect is easily achieved in just 2 sessions (4 weeks apart) using all possible aesthetic injection techniques in the deep layers of the skin.
REMODELING OF THE SKULOSCHALL AND SUB-JUSTOCK ZONES
After 150,000 successful procedures (by December 2016), according to research, the BET (Bioactive Aesthetic Points) technique, specially developed by IBSA specialists for PROFHILO®, is the most common, effective and widely recommended protocol for the restoration of zygomatico-buccal and sub -cheeky-cheek zones.
Preferred by patients according to the following parameters:
- reduced number of sessions;
- the number of injections per session has been reduced, which in turn reduces the level of discomfort;
- reduced cooldown.
BET TECHNIQUE
This technique was created for the lower third of the face due to the predisposition of this area to dermal atrophy caused by the phenomenon of aging.
These 5 points define 5 anatomically receptive zones on the face where large vessels and nerve ganglions are absent, thus minimizing risks and maximizing product diffusion into the zygomatico- and sub-zygomatic areas.
PHOTOS BEFORE AND AFTER PROFHILO®
COMBINING WITH ALIAXIN® HYALURONIC FILLER: PHOTO OF RESULTS
PROFHILO has significant potential for synergistic combinations with ALIAXIN® hyaluronic fillers for volume enhancement.
Learn more about the success of the unique Profhilo® and Aliaxin® and get answers to all your questions, we invite you to visit the scientific-practical IBSA conference "Formula for correction of delicate zones", which will be held on April 20, 2017 in Kyiv.
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