Post-castration (postovariectomy) syndrome is a complex of symptoms that a woman feels after surgical removal of the ovary or after the function of the ovary is turned off as a result of a pathological process in it. The same symptoms are observed in women with physiological menopause, when the ovary ceases to function after involutive changes. In both cases, a woman feels a lot of unpleasant symptoms that greatly impair her quality of life. Post-castration syndrome can and should be treated. See our article for symptoms after ovary removal and methods of treating castration syndrome.
Why are many processes disturbed after ovary removal?
This syndrome may not develop in all women who have been operated on the pelvic organs. The frequency of the syndrome after surgery on the pelvic organs is 60-80%. When the ovary is removed, the syndrome always develops.
Radiation castration or operational shutdown of ovarian functioning leads to disruption of complex processes in the neuroendocrine system, which provoke breakdowns in adaptation mechanisms. Adaptation of the body is provided by the adrenal cortex, which perceives the removal of the ovary as a stress for the body and reacts accordingly. The production of glucocorticosteroids and androgens is activated. In women who have an unstable hypothalamic - pituitary system, post-castration syndrome always develops after removal of the ovary. This number includes women of premenopausal age, because with age-related involution, ovariectomy provokes a breakdown in adaptation processes.
What happens in the body after ovary removal?
After the removal of the ovaries, an acute estrogen deficiency occurs, which causes a sharp increase in the level of gonadotropins, especially FSH. At the same time, symptoms develop that are characteristic of menopause, and it proceeds with a more severe course. Estrogen receptors are found not only in the reproductive organs, but also in the central nervous system, myocardiocytes, vascular endothelium, urogenital tract, connective tissue, bone tissue, oral mucosa, conjunctiva, larynx, and large intestine. Therefore, with estrogen deficiency, systemic changes appear in many organs and tissues. This leads to metabolic changes, the health status and quality of life of a woman worsens.
After removal of the ovaries, postovariectomy syndrome develops in all women. Symptoms appear 2-3 weeks after surgery, in some cases manifestations are possible already 3 days after surgery. The most pronounced symptoms of postovariectomy syndrome are observed 2-3 months after surgery. This condition can persist for many years if the woman does not treat the syndrome.
Symptoms after spaying and menopause
Clinical symptoms that accompany a woman during menopause and after ovary removal are divided into 3 groups:
• Psycho-emotional - memory impairment, depression, irritability, unreasonable fear, sleep disturbance and insomnia, fatigue, addiction to tearfulness.
• Neurovegetative - headache and dizziness, hypertensive crises, pain in the cardiac region, tachycardia, hot flashes, sweating, numbness in the limbs.
• Exchange - endocrine - pain in the bladder during urination, atrophic colpitis , obesity, changes in hair and skin.
In the first time after the operation of removal of the ovaries, neurovegetative symptoms are most pronounced, especially hot flashes. At the same time, the vessels of the face and upper body expand sharply. This is accompanied by a feeling of suffocation, fainting. Hot flashes worse at night, in summer and after meals.
At menopause and a few months after the removal of the ovaries, atrophic changes develop in the genital organs: the uterus decreases in size, the glands stop secreting secretions, the cervical canal closes. The vagina narrows, its walls become dry and thin. In the mammary glands, glandular tissue is replaced by fatty tissue.
Influence of a woman's health status before ovarian removal on the course of the syndrome
After the removal of the ovaries, the symptoms of the psycho-emotional sphere are most pronounced. The severity of the clinical manifestations of post-castration syndrome depends on the health and condition of the woman before surgery or menopause.
So, women with extragenital pathology tend to have a severe course. At the same time, the course of concomitant diseases worsens. The most severe course is observed when the unaltered ovaries are removed. Obesity is more prone to women who were overweight before the removal of the ovaries. This is accompanied by abdominal obesity, an increase in triglycerides, a decrease in high-density lipoprotein levels, an increase in blood pressure, and fasting hyperglycemia. These changes increase the risk of atherosclerosis, strokes, coronary heart disease.
Treatment of the condition after spaying and menopause
Treatment of the condition after removal of the ovaries should be comprehensive. Hormone replacement therapy drugs are prescribed. These are preparations of natural estrogens that contain 17b-estradiol, as well as combined estrogen-gestagen preparations, herbal preparations. The duration of hormone treatment should be at least 3 months. When the drugs are discontinued, the symptoms return again, so treatment in small doses is continued until the onset of natural menopause.
Physical methods are prescribed for hormonal treatment - iodine-bromine, pearl, oxygen, carbonic baths, galvanization of the cervicofacial region. Disaggregants, anticoagulants and hepatoprotectors are prescribed based on coagulogram data.
But, if the removal of the ovaries was performed for malignant neoplasms of the mammary glands or genital organs, taking hormonal drugs is contraindicated. In such cases, symptomatic therapy is prescribed - vitamins, sedatives, physiotherapy and restorative drugs. Such patients should be under the supervision of a doctor.
Share:
Add a comment