Two in one: filler based on calcium hydroxyapatite and hyaluronic acid

The role of dermal fillers for the aesthetic medicine specialist cannot be overestimated. Finding the perfect filler isn't always easy, and many clinicians are wondering, "Is there a perfect filler? Is it possible that the advantages of the most popular groups of fillers are combined in one preparation?

Currently, two groups of fillers are most in demand among aesthetic medicine specialists: based on hyaluronic acid and based on calcium hydroxyapatite. Both groups have their advantages and disadvantages.

At estet-portal.com we will analyze

what are the pros and cons of these products, as well as talk about a new filler that combines the positive properties of hyaluronic acid and calcium hydroxyapatite.

Advantages and disadvantages of calcium hydroxyapatite fillers

Fillers based on calcium hydroxyapatite have gained wide popularity among specialists and patients due to the effects:

•    stimulation of neocollagenesis;

•    immediate and long-term delayed results (up to 2 years);

•    volumizing and lifting effect.

But the lack of a specific enzyme capable of solving the problem of tissue ischemia in the event of vascular complications limits the use of these fillers and requires high professionalism of the doctor.

Inna Stadnik: Injection procedures today – this is a sign of good manners

Advantages and disadvantages of hyaluronic acid fillers

Hyaluronic acid fillers have their own advantages:

•    biocompatibility and biodegradation;

•    Different viscosity of preparations provides the ability to work in any, even the most delicate areas;

•    obtaining the optimal result: from a soft, plastic effect to a clear contouring;

•    presence of hyaluronidase antidote allows you to quickly and effectively eliminate complications.

The conditional disadvantages of hyaluronic acid-based fillers include the relative short-term effect (on average from 3 to 9 months) and, accordingly, the need for frequent repeated injections to maintain the effect, as well as the ability in some cases to cause swelling at the injection site of the filler.

Innovation, Efficiency, Reliability: 3 Reasons to Choose a Plasma Machine

Strength in unity: a unique new generation filler

Luminera Derm (Israel), a member of the Panaxia LTD group, has developed a filler that combines the main advantages of both hyaluronic acid-based fillers and calcium hydroxyapatite-based fillers due to its unique composition.

HArmonyCа – the world's only new-generation filler for contouring designed to restore natural volumes and model facial contours, based on a composite matrix consisting of cross-linked hyaluronic acid and calcium hydroxyapatite microspheres.

HArmonyCа promotes the synthesis of endogenous collagen, provides a long-term rejuvenating effect, volumization and skin lifting.

Composition of the preparation:

•    Microspheres calcium hydroxyapatite (55.7%), diameter 25 - 45 microns;

•    Sodium hyaluronate gel (20 mg/ml), cross-linked (BDDE

•    Phosphate buffer;

•    0.3% lidocaine (also available without lidocaine).

* Available in a pack of 2 syringes × 1.25 ml.

Exclusive distributor of HArmonyCa filler in Ukraine and Moldova –
OKK-EXPERT PHARMA COMPANY.

Synergistic effects of hyaluronic acid and calcium hydroxyapatite

HArmonyCa contains calcium hydroxyapatite and hyaluronic acid. Calcium hydroxyapatite is added during the cross-linking of the components, which ensures the stability of the gel. With the properties of calcium hydroxyapatite fillers and hyaluronic acid fillers, HArmonyCa provides a synergistic effect with excellent results.

The stimulation of collagen production is due to a combination of active ingredients: calcium hydroxyapatite stimulates neocollagenesis, while hyaluronic acid forms a supporting extracellular matrix that stimulates fibroblast proliferation.

Hyaluronic acid, in the structure of which calcium hydroxyapatite microspheres are embedded, prevents the aggregation of calcium hydroxyapatite microspheres. >

Morphology and structure of the composite filler HArmonyCa

The composite matrix of the HArmonyCa filler consists of calcium hydroxyapatite microspheres that are embedded in astructure of high quality cross-linked hyaluronic acid. • Calcium hydroxyapatite microspheres have a round and smooth shape, non-porous structure, which ensures easy extrusion.

• The microsphere diameter (25 – 45 µm) minimizes the risk of particle migration and phagocytosis.

• The inclusion of calcium hydroxyapatite microspheres in the structure of hyaluronic acid helps to maintain a balance in the even distribution of microspheres.

HArmonyCa filler is hyaluronidase sensitive. Hyaluronic acid makes up 70% of the volume of the syringe and can be completely dissolved, destroying the gel structure, in case of adverse events.

The mechanism of action of the HArmonyCa filler

The effect of volumization, smoothing of wrinkles and folds, is observed immediately after the procedure, which is due to the volume of the administered drug and the presence of hyaluronic acid.

2.   Long-term exposure:

Calcium hydroxyapatite microspheres form a scaffold on which fibroblasts settle, and further "fouling" occurs; this scaffold with new collagen fibers. Hyaluronic acid binds to fibrin, stimulating the restructuring of the extracellular matrix.
3.   Filler Biodegradation:

Biodegradation of microspheres of calcium hydroxyapatite and hyaluronic acid occurs synchronously with the enhancement of neocollagenesis, which ensures long-term preservation of the effect and the naturalness of the result. Subsequently, the decay products of the filler are completely eliminated from the body.
Read the most interesting articles in
Telegram
!


HArmonyCA BENEFITS:

OKK-EXPERT PHARMA COMPANY

.  

•    The product is based on safe, biocompatible ingredients; •    Does not cause inflammatory and allergic reactions; •    Reduction of side effects in the form of edema, erythema and burning sensation;

•    Is biodegradable, completely eliminated from the body, does not migrate; •    Hyaluronidase sensitive;

•    HArmonyCa filler complies with ISO 9001 and ISO 13485;

•    HArmonyCa filler is registered in Ukraine (No. UA.TR.039.208 dated 05/24/19. Class 3 medical device, injectable soft tissue implant).

Efficiency

•    Possessing the properties of fillers based on calcium hydroxyapatite and fillers based on

hyaluronic acid, HArmonyCa provides a synergistic effect: it promotes the production of its own collagen and stimulates the restructuring of the extracellular matrix.

•    Provides a volumizing and lifting effect.

Practicality

•    Provides both immediate and long-term delayed results, which reduces the frequency of procedures;

•    The ability to dissolve most of the filler with hyaluronidase if necessary.

•    Premium product with excellent value for money.

The product is intended only for professional use by cosmetologists who have completed advanced training in contouring.

Read also:

Jet Plasma Lift Medical: an innovative device for universal use in medicine

Share: