The first description of rosacea dates back to the 15th century. Many well-known scientists have been studying this disease, but despite this, the final cause of its development has not been established. Rosacea is considered a polyetiological disease, because many factors can provoke its occurrence.
Dermatovenerologist, Head of the Department of Dermatovenereology, Doctor of Medical Sciences, Professor Vladimir Petrovich Adaskevich. Rosacea pathogenesis: why the disease occurs
The main triggers of rosacea include:• ultraviolet radiation;
• Influence of the Demodex mite;
• physical or chemical damage to the skin.
Their action promotes the activation of Toll-like receptors, resulting in the release of cathelicidins (antimicrobial peptides) that stimulate chemotaxis and angiogenesis.
In rosacea, mast cells are activated, and as a result, the inflammatory process develops.
Drugs for the treatment of rosacea affect different parts of the pathogenesis of this disease. Thus, understanding the processes underlying this pathology is the key to effective treatment of rosacea.
Vacuum skin cleaning: the principles of the procedure that are important to know Rosacea treatment: when prevention is indispensable
Prevention is of great importance in the complex treatment of rosacea.
Therefore, it is very important to limit the factors provoking this disease:• sun exposure, wind and humidity;
• influence of high temperatures;
• drinking hot drinks and alcohol;
• use of local hormonal preparations;
• heavy physical activity.
It is also very important to be careful when choosing cosmetics for facial care. For rosacea, it is advisable to avoid any products containing alcohol, fragrances and substances that stimulate blood flow to the skin.
ABC of the skin for a cosmetologist: the structure of the dermis Characteristic features of the main clinical subtypes of rosacea
In order to prescribe an effective treatment, it is necessary to understand which subtype of rosacea you are dealing with. Each of the forms has its own characteristic features.
1) Erythematous teleagniectatic subtype;
Persistent erythema appears on the skin, which has a centrofacial position: in the forehead, chin, cheeks. Telangiectasias can be found on the skin. The appearance of these signs is accompanied by burning and tingling.
Characterized by the presence of papules and pustules, which are most often located in the forehead, cheeks and chin. However, sometimes there are also rare localizations: at the border of hair growth, behind the ears, on the neck and chest.
3) Phymatous subtype; , chin, forehead, ears and eyelids.
Baba Yaga's nose or what is rhinophyma
4) Ophthalmic rosacea. Damage to the periorbital region, which is accompanied by redness of the eyes visual impairment and photophobia.
• metronidazole 0.75 or 1%;
• azelaic acid gel;
• permethrin cream;
• calcineurin inhibitors;
• brimonidine tartrate gel.
The selection of local therapy should be carried out individually, depending on the characteristics of the patient's skin.
Brimonidine tartrate has a pronounced and rapid effect, relieves redness, however, it lasts no more than 12 hours.
Systemic treatment of rosacea includes antibiotic therapy (macrolides or tetracyclines), systemic metronidazole.
Rhinophyma Treatment — it is a long and complicated process. At the first stage, tetracycline per os and isotretinoin are prescribed. In the second stage, dermabrasion and vaporization are recommended. The third stage requires surgical treatment.
Laser skin dermabrasion: an effective procedure for a young and attractive face
Therapy for rosacea should be complex and regular. The main task of the doctor, when working with such patients, is to prevent the recurrence of the disease and its further progression.
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