Why Radiesse? Benefits of working with the original preparation based on calcium hydroxyapatite

Injectable preparations based on calcium hydroxyapatite are gaining more and more confidence in the cosmetic market, as they allow achieving excellent rejuvenating results. However, not all such drugs have undergone proper clinical trials, which means that their safety for the health of patients can be questioned. How can an original calcium hydroxyapatite preparation differ from other preparations containing calcium hydroxyapatite, and why Merz Aesthetics can vouch for the quality of Radiesse, read on estet-portal.com.

Features of the original drug Radiesse based on HAC

Let's clean up the definitions

Original drug — this is a drug that was created on the basis of a new substance, synthesized for the first time or obtained from natural raw materials, passed a full course of preclinical and clinical studies of efficacy and safety and is protected by a patent for a certain period, in Ukraine — 20 years old.

Generic — this is a follower, a drug that appeared after the expiration of the patent. Minimizing production costs and using the cheapest ingredients results in what every doctor knows — too cheap drugs do not work! Quality generic can't be cheaper!

Radiesse Lifting Filler received the European Certificate (EC) of Conformity for Plastic and Reconstructive Surgery in 2003. This drug was approved by the FDA two years later for use in such indications as facial augmentation, correction of deep wrinkles and improvement of skin quality, and in 2015 — to replenish the lost volume of tissues of the back of the hands.. In 2011, the Ministry of Health of Ukraine was registered.

More than 6,000,000 syringes sold worldwide by 2016.

Triple effect  Radiesse  is explained not only by the excellent biocompatibility of the drug with the tissues of the human body, but also by the unique action of the active components — calcium hydroxyapatite microspheres.

The unique Radiesse production technology, when calcium hydroxyapatite is processed in vacuum - without oxygen access, and therefore without the risk of oxidation – allows you to get a completely white substance. At the same time, calcium hydroxyapatite microspheres get a rounded shape with a smooth smooth surface and a particle diameter  25 – 45 microns. Microspheres of a different size are screened out during production. Microspheres are stable and unchanging, including  when diluting the drug for injection. A number of clinical studies have shown that it is this calcium hydroxyapatite particle size that is optimal for stable presence in the area where the original Radiesse preparation was injected, and for its gradual, problem-free biodegradation.

Externally, some preparations containing calcium hydroxyapatite often have a grayish tint, which is probably due to the peculiarities of technological production, which allow redox reactions. When a substance is oxidized, as a result of the return of electrons, its oxidation state increases. As a result of this process, the drug acquires a gray color. Also, when oxidized, the molecule of the original substance can become unstable and break up into more stable and smaller components.

The effect of the injection of a drug with different microsphere diameters can be unpredictable: particles of a substance with a diameter of up to 25 microns can enter the vascular bed and create a risk for internal organs, where they will be brought with the blood stream, and particles larger than 45 microns can damage when injected with the drug fibroblasts and become a possible cause of pathological fibrosis.

Not all manufacturers of drugs containing calcium hydroxyapatite can boast of the results of clinical studies that would confirm the effectiveness and safety  drugs, and therefore, when working with patients, you should choose the original drug that has already proven itself in the market and has scientific evidence of its effectiveness. This can be called Radiesse from Merz Aesthetics.

Why cosmetologists choose Radiesse

By 2016, over 6,000,000 Merz Aesthetics Radiesse syringes had been sold worldwide. This success indicates that doctors and their patients are convinced of the high efficiency and safety of the original drug, making an informed choice in favor of Radiesse.

Radiesse dermal filler's excellent quality rating and all of its claims have been confirmed by more than 200 clinical studies, which are available in relevant scientific publications, which provide data on more than 4000 patients worldwide.

According to Merz Aesthetics, more than 90% of patients after insertion  Radiesse noted absolute satisfaction with the result & nbsp; 12 months after the procedure.

It is important to note such qualities of the original Radiesse preparation as:

• Lifting filler Radiesse® is one of the safest dermal fillers available on the market.
• Excellent tolerability and clinically proven safety.
• 90% satisfied patients after 12 months.
• Trusted worldwide with over 6 million syringes supplied.

To date, no calcium hydroxyapatite manufacturer other than Radiesse has provided physicians and their patients with similar scientifically validated data on the efficacy and safety of their products. Concerned about the health and well-being of their patients, about the good result of the procedure, the doctor should weigh all the possible risks and make a choice in favor of the original drug, for the reliability of which its manufacturer is ready to be responsible.

This review of the drug begins a series of articles on the effectiveness of Radiesse in augmentation, lifting and contouring of the soft tissues of the face and body, as well as on the safety of using the drug in injectable cosmetology.