Применение высоких доз ботулотоксина в коррекции глабеллярных морщин

Correction of mimic wrinkles with the help of botulinum toxin preparations has been one of the most successful and sought-after cosmetic procedures for many years. Injection of botulinum toxin into certain areas of the face leads to relaxation of the contracted muscles, creating the effect of smoothing wrinkles.

One of the most common reasons patients visit cosmetologists is the appearance of wrinkles in the glabella area, which gives the face a somewhat gloomy, “mature” look. view.

The results of a study concerning the use of higher doses of botulinum toxin preparations have opened up new possibilities and perspectives in the use of botulinum toxin in the correction of glabellar wrinkles. Read more on estet-portal.com in this article.

Mimic wrinkles: why vertical glabellar lines appear

Frowning – it is a natural element of the mimic activity of any person. For the process of "frowning" the frontalis muscle is mainly responsible. Compressing in a downward direction, it leads to the temporary formation of vertical skin folds between the eyebrows. This creates a characteristic frown on the face.

With age, in many patients, in place of the "folds of frown" permanent hyperfunctional lines are formed, known as glabellar wrinkles.

Since the main mechanism for the development of glabellar lines is the hyperfunction of the frontalis muscle, the use of the muscle relaxant properties of botulinum toxin is pathogenetically justified.

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Perhaps the only, but quite significant problem with the use of botulinum toxin preparations in the correction of glabellar wrinkles was the short duration of the effect after the procedure.

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Results from a study on the use of higher doses of botulinum toxin

The results of Allergan's study on the use of higher doses of BOTOX®; in the correction of glabellar wrinkles – this is an incredible discovery in the beauty industry, which opens up new possibilities in the use of botulinum toxin preparations.

The purpose of the study was to evaluate the duration of effect and the safety of using higher doses of BOTOX® preparations: 40, 60 and 80 units. The results were compared with those obtained using 20 units. BOTOX®.

The follow-up period was 24 weeks. The study involved 226 patients.

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High doses of botulinum toxin provide longer duration of effect

The results of a study on the use of higher doses of botulinum toxin in the correction of glabellar lines confirmed the hypothesis that higher doses of botulinum toxin give a longer effect in the correction of glabellar lines.

Higher doses of botulinum toxin give a longer lasting effect in the correction of glabellar lines.

Doubling the dose of BOTOX® increased the duration of the botulinum therapy treatment to 24 weeks in about one third of patients.

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It should also be noted that a study on the use of high doses of botulinum toxin in the correction of glabellar wrinkles confirmed the safety of this technique. There was only 1 case (0.4%) of eyelid ptosis with 80 units of BOTOX®, which is the same as the complication rate with 20 units (also 0.4%).

Secrets of Success: Botulinum Toxin – best doctor assistant

The results of this study play an important role for practicing cosmetologists, as they open up new possibilities and prospects for the use of BOTOX® preparations.

Exclusive interview with a doctor of the highest category, dermatovenereologist, cosmetologist Igor Rudenko, read the newest and most useful information about the use of high doses of BOTOX® in the correction of glabellar wrinkles.

Stay up to date with the latest and most interesting events thanks to the "News" section. You may also be interested in: Immunogenicity of botulinum toxin preparations: how to avoid the formation of antibodies.

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