Retinoids for the skin with low irritant potential and high efficiency

Skin aging processes are directly related to age-related degeneration of fibroblasts – cells that synthesize components of the extracellular matrix, including collagen and elastin. A hallmark of aging skin – violation of the homeostasis of the collagen matrix as a result of changes in the structure of fibroblasts (cells increase in size, become flatter and more rigid). An effective method of influencing these cells and fighting the signs of aging is the use of retinoids for the skin.

What retinoids are included in MEDICARE cosmeceuticals?

Retinode – a group of vitamin A derivatives of natural or synthetic origin. Retinoids are lipophilic and easily penetrate the skin through the stratum corneum and excretory ducts of the glands. In the skin, these substances act as follows:

• in the epidermis – control the processes of keratinization and pigmentation;
• in the dermis – stimulate the restoration of the extracellular matrix, which is destroyed as a result of aging processes and exposure to external factors.

MEDICARE uses the retinoid cascade method in its skin care program.

The MEDICARE Retinol Skin Care Program uses:

1. Retinyl palmitate: acts on the structure of the skin, smoothes wrinkles, stimulates collagen synthesis and skin cell renewal.
2. Retinyl acetate: accelerates the process of exfoliation of dying cells, increases the production of collagen and elastin fibers.
3. All-trans retinol: increases skin density, increases collagen synthesis, improves skin hydration, improves skin structure.

MEDICARE uses the retinoid cascade method in its skin care program. The essence of this method is the effect of retinoids of varying degrees of chemical activity at different levels of the derma-epidermal junction.

Retinoids for the skin: mechanism of action of vitamin A derivatives

Retinoid molecules penetrate the cell membrane by non-receptor endocytosis. A key role in the bioavailability of retinoids for the skin is played by the cellular retinoic acid binding protein (CRABP), which allows the rapid penetration of vitamin A derivatives into the cell nucleus.

Retinoid receptors – RAR and RXR – provide a direct action of retinoids, as they bind to specific DNA regions and activate certain regions of the – retinoid-specific elements (RRE).

Retinoids affect the growth of epithelial cells, their differentiation and functional activity, prevent the destruction of existing collagen in the skin and stimulate the synthesis of new collagen fibers.

MEDICARE Cosmeceuticals: Retinoids for maximum skin efficacy

The main feature of MEDICARE cosmeceuticals is the use of the retinoid cascade method: the biological activity of retinoids is provided by a significantly lower concentration of these substances than in drugs.

Medicines included in the MEDICARE Retinol Skin Care Program:

1. Perfecting Night Eye Serum – Retinol Eye Serum 0.3%

Active ingredients of the serum:

• all-trans retinol 0.3%;
• tocopherol acetate (vitamin E);
• jojoba oil.

Readings:

• regular anti-age eye care;
• dermal matrix restoration;
• signs of photoaging;
• preparation for peels;
• preparation for the retinol care program.

Action:

• stimulation of collagen synthesis;
• skin tightening;
• increase in hyaluronic acid content;
• skin lightening;
• Improve skin texture and appearance.

2. Perfect Night Serum – Retinol Serum 0.6%

Active ingredients of the serum:

• all-trans retinol 0.6%;
• tocopherol acetate (vitamin E);
• jojoba oil.

Readings:

• daily anti-age facial treatment;
• acne control;
• fight against the signs of photoaging;
• restoration of the dermal matrix.

Action:

• reduction of signs of skin aging;
• improving skin tone;
• lightening hyperpigmentation;
• fight against hyperkeratosis;
• acne removal;
• regulation of the sebaceous glands;
• improvement of skin texture and color;
• improves skin hydration.

3. Retinol Perfecting Concentrate – Retinol Concentrate 2%

Concentrate active ingredients:

• all-trans retinol 2%;
• tocopherol acetate (vitamin E);
• jojoba oil.

Important! This product is to be used exclusively with Hydrant Night or Hydrant Serum.

Action:

• stimulation of collagen synthesis;
• increased hyaluronic acid content;
• wrinkle smoothing;
• acceleration of the cell exfoliation process;
• stimulation of new cell growth.

Topical retinoids are contraindicated during pregnancy and lactation.

MEDICARE's retinoid skin preparations have a low irritant potential and are highly effective. By following a special skin care program based on the retinoid cascade method, you can achieve excellent anti-aging results (restor skin elasticity, hydration, significantly reduce the severity of wrinkles, acne and hyperpigmentation), without damaging the skin. To learn more about the retinoid cascade regimen and purchase products for professional and home anti-age skin care, contact the manufacturer – MEDICARE.