Androgenetic alopecia – this is one of the most common diseases that trichologists have to deal with in their practice almost daily. 95% of all cases of male pattern baldness and, according to various sources, from 20% to 90% cases of hair loss in women are due to this particular pathology. In this article, estet-portal.com talks about a modern algorithm for the treatment of androgenetic alopecia. What drugs are currently approved and widely used throughout the world, and what results can be expected from their use – find out now.
Drugs for the effective treatment of androgenetic alopecia
Androgenetic alopecia – this is a hereditary pathology, which is hair thinning under the influence of male sex hormones – androgens.
Androgenetic alopecia can occur according to the male type, when the hair falls out with an accentuation in the fronto-parietal zone, and according to the female type, characterized by thinning and diffuse hair loss throughout the head.
Modern treatment of androgenetic alopecia involves the use of drugs approved worldwide. But before starting treatment, the specialist must understand what is happening in the patient's scalp.
Androgenetic alopecia treatment:
- what happens in the scalp with androgenetic alopecia;
- minoxidil drug for the treatment of androgenetic alopecia;
- The drug finasteride for the treatment of androgenetic alopecia.
What happens in the scalp with androgenetic alopecia
In androgenetic alopecia, under the influence of androgens, the following processes occur in the skin of the patient's scalp:
- perifollicular inflammation develops due to internal and external influences;
- against the background of inflammation, autoimmune reactions of varying severity occur;
- occurs overgrowth of connective tissue: scarring and fibrosis;
- susceptibility of the skin to irritants increases and the functional viability of the epidermal barrier decreases;
- circulation of blood and lymph is disturbed;
- prooxidant shift occurs;
- tissue respiration is disturbed;
- local susceptibility to testosterone metabolites increases;
- hyperkeratosis occurs;
- energy status is decreasing.
Minoxidil drug for the treatment of androgenetic alopecia
The European Medicine Agency and the US Food and Drug Administration have long approved minoxidil for the treatment of androgenetic alopecia, which continues to prove effective today. In spray, foam or gel form, minoxidil is one of the most effective topical treatments for androgenetic alopecia. Minoxidil has passed all the necessary clinical studies. It has been proven that when using 2% minoxidil, hair growth increases by 8%, and 5% minoxidil – by 10-20%. However, it should be remembered that in some patients sensitivity to the drug may be reduced.
The drug finasteride for the treatment of androgenetic alopeciaFinasteride – this is another drug for the treatment of androgenetic alopecia, which has also undergone a number of clinical studies and has been approved by the European Medicine Agency (European Medicine Agency) and the US Food and Drug Administration. Finasteride – an internal drug that inhibits the action of type 2 5-alpha reductase, reduces serum, prostate and scalp DHT levels, increasing hair growth by an average of 6% after two years of use. However, finasteride is not indicated for women of reproductive age.
The modern concept for the treatment of androgenetic alopecia implies an integrated approach to the problem, including a combination of drugs, cosmetics, injection methods, physiotherapy techniques.Thanks to this approach, it is possible to solve the problem of androgenetic alopecia as effectively as possible, restoring the patient's former beauty and health to the hair. Read in the section "Trichology" estet-portal.com has more
articles about alopecia.
Add a comment