The unique properties of the Juvederm® range: the possibilities of Vycross™ technology

The hyaluronic acid molecule has long been known to science and has been used in aesthetic medicine for a long time to eliminate the signs of facial aging. This substance is used as a basis in the manufacture of various fillers, the purpose of which is volumization, smoothing wrinkles and improving skin quality. However, the properties of the drugs and, accordingly, the final result of their use and the duration of the effect also depend on the technology used to obtain the anti-age product.

About the features of the unique technology Vycross™ and the Juvederm® product line; in an interview for estet-portal.com said Pierre Lebreton (Pierre Lebreton) – PhD, director of filler research and development at Allergan.

Pierre Lebreton – PhD, Director of Filler R&D at Allergan

What is the uniqueness of Vycross™ technology?

PL Uniqueness of Vycross&trade technology; is that it provides more effective cross-linking of hyaluronic acid and, accordingly, new properties of preparations: they provide a more pronounced lifting effect, and are also characterized by better distribution and plasticity. Preparations made using this technology are better integrated into tissues, absorb less water, have a uniform structure and are characterized by low extrusion force. There is a wealth of clinical evidence supporting the efficacy and safety of these products.

What are the benefits of the new Juvederm® syringes?

New Juvederm® more ergonomic. Such instruments reduce fatigue and facilitate the suction process, allowing it to be performed with one hand.   New Juvederm® more ergonomic - they reduce fatigue and facilitate the suction process.

Hylacross™ and Vycross™?

  Hylacross™ and Vycross™ there are similarities and differences. Both technologies provide cohesiveness and homogeneity of the gels produced with their help. And the difference between them lies in the effect that can be achieved: by changing the parameters of cross-linking, we can increase the effectiveness of HA cross-links. As a result we get:

• gel absorbs less water;
• better integration of the material into the fabric;
• excellent filler spreadability;
• low extrusion force.
In terms of rheological properties, more efficient crosslinking will increase the volumization capacity of the formulation (eg, as is the case with Juvederm® Voluma®). And also, due to the excellent plasticity of the material, this allowed the creation of lighter products, such as Juvederm® Volbella™.

Allergan get hyaluronic acid, and how does the Vycross™ line get from it?

  We have been working in this field for over 20 years. We started to develop and produce HA preparations for medical use. Of course, in the production of such products it is very important to use high-quality raw materials (HA). Therefore, all materials used by Allergan are in the pharmaceutical grade – this is necessary for security. For about 17 years we have been producing the best cross-linked HA preparations for aesthetic procedures.

Juvederm® Is Volite™ the same as in all Vycross™ preparations?

  With regard to the structure of Volite®, the same cross-linking process is used to form it as for other products in the Juvederm® line. However, special mixing parameters apply during the production of this drug. Because the Volite™ used to improve the quality of the skin, it has characteristics that distinguish it from the rest of the products in the line.

Allergan manufacture the Juvederm® First Generation to Ultra?          

  Of course, we produce products of several generations. For example, first-generation fillers are no longer manufactured – they were replaced by second-generation drugs. As for the line of products produced using Vycross™ technology, they belong to the third generation, the first of which was the Voluma™ filler introduced in 2006.   Vycross™ characterized by a lower concentration of HA, and this allows you to get an effect lasting up to 24 months – this highly effective three-dimensional structure of hyaluronic acid is more resistant to degradation.

Vycross™ product line into fabrics?

  We believe that one of the reasons for the excellent integration into tissues is the uniformity of the gel structure, as well as its excellent spreadability and plasticity. It is these properties that are part of the formula for natural tissue integration.

Vycross™ line last up to 24 months?

  We were able to achieve this duration of action due to the higher efficiency of cross-linking and the formed structure of the HA. The Vycross™ characterized by a lower concentration of HA, and this allows you to get an effect lasting up to 24 months – this highly effective three-dimensional structure of hyaluronic acid is more resistant to degradation.

  First – understand the product, attend all trainings and courses that allow you to get detailed information about the product and its properties from the point of view of science. Second – constantly take care of security, i.e. observe hygiene standards, follow only the best practices. As for patients, they should also be informed about product features and technologies.

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