Возможности комбинации  аппаратных и инъекционных методик для коррекции клинических проявлений розацеа

When treating rosacea, a cosmetologist has to consider various options for combined therapy, since at different stages of this disease, some correction methods are more effective, while others – completely unacceptable. Most often, hardware procedures and injection correction are combined using Meso-Xanthin F199™.

This combination allows, according to estet-portal.com, to influence the initial stages of the manifestation of the disease and allows  achieve stable remission and significantly improve the patient's skin condition.

Peculiarities of the injection correction technique in the complex therapy of rosacea

According to some experts, the development of rosacea is determined by congenital increased susceptibility to irritating environmental factors, the activity of immune cells, proteases, antimicrobial peptides, inflammatory mediators, and many other factors.

As a result of this activity:

  • Persistent redness develops, mainly of the skin of the central part of the face;
  • Persistent expansion of small and superficial vessels is formed;
  • Papules, pustules are formed and swelling of facial tissues is observed;
  • This leads successively to hypervascularization, inflammation and hyperplasia of the connective tissue and sebaceous glands.

Congenital susceptibility to harmful environmental factors, diseases of the gastrointestinal tract, endocrine disorders, and the role of Demodex folliculorum mite can be provoking factors for the development of the disease. According to new trends in the coverage of pathogenesis, the leading role is determined by the reactions of the innate immunity of the skin with an increased content of cathecilidine.

All of the above factors lead to the development of chronic inflammation, dysregulation of neurovascular connections in the skin and neoangiogenesis, damage to the architecture of the intercellular matrix. Clinically, persistent erythema is formed, against its background of telangiectasia, inflammatory papules and pustules are formed, and in the late stage with a severe course - phymatous changes. 

Depending on the factors that provoked the manifestation of rosacea, as well as the degree of the inflammatory process and concomitant diseases, the doctor determines a set of therapeutic measures.
from Emet
. Meso-Xanthin F199™ has an anti-inflammatory effect, epigenetically regulates collagen production and has a high antioxidant activity.

The properties of the drug, allowing it to be effectively used in rosacea, are due to the inclusion of the unique carotenoid Fucoxanthin F199 in its composition. This carotenoid reduces vasodilation, normalizes collagen production, inhibits inflammation and reduces cellular infiltration.

In addition to the carotenoid, the preparation contains other components that have proven themselves in the treatment of rosacea – copper peptide, vitamins C and E, epidermal and insulin-like growth factors, hyaluronic acid.

Thanks to the active substances Meso-Xanthin F199™ it is possible to significantly reduce erythematous manifestations, improve skin tone and elasticity, reduce the severity of the vascular pattern on the skin of the face and prevent the development of inflammation.


The drug is applicable for patients from the age of 18, this allows you to start therapy as early as possible and prevent the progression of rosacea to more severe stages. However, at that stage of the disease, when the skin is abundantly affected by papules and pustules, or has phymatous changes  injection therapy should be replaced or combined  with  hardware procedures and obligatory specific dermatological treatment.

Possibilities of hardware methods for correcting the manifestations of rosacea

Combination of injection procedures in the treatment of rosacea with hardware techniques – an integral part of complex therapy.

• Laser therapy.

Considered one of the most effective treatments for rosacea. IPL technologies are used for secondary erythema and telangiectasias that persist after regression of the inflammatory phenomena of rosacea. Light waves penetrate the epidermis, reaching ectatically dilated vessels, leading to thermolysis of their endothelium. The blood flow in the damaged vessels stops, and within 2-3 weeks they are obliterated, thereby reducing the clinical manifestations of erythema and rosacea. • Cryotherapy.
It has an anti-inflammatory, vasoconstrictive anti-demodectic effect and is indicated for patients, regardless of the stage of the disease. The first procedure of cryomassage with liquid nitrogen is usually carried out very carefully, preventing the development of acute dermatitis, duration of exposure is not more than one second. Applications are carried out every other day until deep exfoliation of the skin. Course 10-15 procedures. This treatment reduces infiltration around the vessels and follicles. • Electrocoagulation.
It is used to destroy telangiectasias, papular and papulopustous elements using high frequency currents. Electrocoagulation occurs upon contact with the tissue of the active electrode, which is shaped into a sharp needle, knife, ball, etc. In the erythematous and limited papulo-pustular stage of rosacea, as a rule, a complete clinical cure is achieved. corrections, but the terms and possibilities of combination of techniques may vary depending on the condition of the patient's skin. hardware procedures and injection of Meso-Xanthin F199™ by Emet

– allows you to reduce the manifestations of erythema, the severity of telangiectasias, prevent the development of inflammation and the progression of the disease in general, improve & nbsp; skin quality, achieve a state of stable remission and improve the quality of life of the patient.
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– allows you to reduce the manifestations of erythema, the severity of telangiectasias, prevent the development of inflammation and the progression of the disease in general, improve & nbsp; skin quality, achieve a state of stable remission and improve the quality of life of the patient. xxxx>™ – allows you to reduce the manifestations of erythema, the severity of telangiectasias, prevent the development of inflammation and the progression of the disease in general, improve & nbsp; skin quality, achieve a state of stable remission and improve the quality of life of the patient.

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