The most sensational discoveries of 2015 that will help prolong youth

The search for a universal and harmless way to prolong youth and preserve beauty for many years does not stop. 2015 was rich in interesting discoveries in the field of anti-age technologies, estet-portal.com has selected for you the top 5 promising projects, discoveries and experiments, thanks to which the fight against aging of the human body as a whole will reach a new level: telomerase activation, « 'anti-aging pills', applications, computer programs and DNA methylation analysis.

Discoveries of 2015 that will help prolong youth

It is not the first year that experts have been looking for ways to prolong youth not only of the skin, but of the whole organism. Below are the main events of 2015 that have become a real sensation in the field of anti-aging.

1. Prolong youth by activating telomerase

Elizabeth Parrish – researcher from America – in the fall of 2015, she decided on a rather bold experiment: the intravenous injection of genetic material. After penetrating into the nucleus of each cell, the material was supposed to start the process of rejuvenation of the body. At the same time, Elizabeth Parrish herself emphasized that her goal is not to get rid of wrinkles, but to rejuvenate the body in general and try to avoid diseases associated with aging. The essence of the expected changes is the activation of telomerase – an enzyme that restores the length of telomeres (those very end sections of chromosomes that ensure the integrity of DNA and its stability). Using this method, scientists expect to prolong youth by rejuvenating the red bone marrow, which is responsible for blood formation and the power of the immune system.

2. An anti-ageing pill in one tablet

At the end of November 2015, clinical trials of so-called anti-ageing pills were given the green light. Over the course of 5 years, starting next year, researchers will analyze the effect of the drug for treating diabetes on the general condition of the body. Nir Barzilai started taking metformin when doctors diagnosed him as having a pre-diabetic condition. When Nir Barzilai's indicators returned to normal, he did not stop taking the pills because, in his opinion, these drugs can protect the body from aging-related disorders. Nir Barzilai – director of the Institute of Gerontology at the Albert Einstein College of Medicine in New York. He decided to prolong youth with the help of metformin and specially developed a program of clinical studies that will be carried out on volunteers.

3. Computer program "Geroscope"

Andrei Garazh, an expert in biomedical technology and research, took part in the development of a special computer program designed to test potential "anti-aging drugs". The development takes place within the framework of the international scientific and medical project Insilico Medicine. Andrei Garazh explained that the activity of signaling pathways, through which information important for life processes is transmitted inside cells, decreases with age. Failures in cellular mechanisms lead to human aging. The scientists plan to identify differences in the signaling pathways of young and senescent cells in order to isolate an aging biomarker. In the future, experts plan to influence cells with various substances,

4. Digital anti-age beauty contest

As part of a project to create an international database of human faces, bioinformaticians have developed special applications for smartphones. With the help of one of these applications, you can take part in a beauty contest, which will be judged by robots. Their task – choose the queen and king of beauty in different age categories according to the criteria of youthful face. The scientific interest in such a peculiar beauty contest is explained by the following: robots will learn to recognize and evaluate the parameters of faces, as a result of which it will be possible to create an accurate biomarker of aging in the face. Another application that will help prolong youth is aimed at the analysis of wrinkles. The purpose of such an application – determination of the rate of aging and analysis of the effectiveness of anti-age face care products.

5. DNA methylation analysis – studying the biological clock of aging

DNA methylation – this is the process by which methyl groups attach to certain regions of DNA and affect the activity of genes. Recently, a connection has been found between the location of such methyl groups directly in DNA and the biological age of a person.

Based on the use of DNA methylation models, it is possible to most accurately determine the biological age of a person. This technology was developed by Professor Steve Horvath (University of California, Los Angeles). Thanks to this technique, the following important patterns of aging were identified:

Obesity, HIV and Down's Syndrome accelerate the aging process.

1. The aging process is slowest in the cerebellum.
2. Cancer cells can age faster or slower than the cells from which they originated.
Experts have high hopes for DNA methylation analysis, which they hope will accurately determine the influence of various factors (diseases, drugs, nutrition, etc.) on human lifespan.

Estet-portal.com hopes that scientists will be able to achieve their goals and develop effective methods that will help prolong youth and protect humanity from age-related diseases.