Cheilit is an inflammation that appears on the lips and can affect the skin, mucous membranes, or red border of the lips. But one of the varieties of cheilitis has features and was first described in the 1930s by the Italian dermatologist Manganotti. This type of cheilitis affects only the red border of the lips, and the lower lip suffers mainly. Suffer from Manganotti's cheilitis & nbsp; mostly older men. The peculiarity of this type of disease is that without timely proper treatment, cheilitis turns into lip cancer.

Why Manganotti cheilitis develops and how it manifests itself

Cheilit Manganotti is based on a violation of cellular metabolism in the skin and mucous membranes of the lips. Lip injuries predispose to the development of cheilitis (both instantaneous and in the form of permanent mild injury due to incorrectly selected dentures or crowns, poorly treated teeth). Manganotti cheilitis can be provoked by impaired digestion and vitamin A deficiency in the body, strong insolation, especially if the lips have been sunburned or dried out for a long time under the active sun.

Manganotti cheilitis, or abrasive precancerous cheilitis, manifests itself  in the form of one, less often two or three erosive lips, located on the sides or sometimes in the center. These defects have the shape of an irregular oval, rich red color, smooth surface. Sometimes on the surface of such erosion there may be a crust that is difficult to remove, and bleeding immediately appears in its place. Erosions are most often located on a smooth, unchanged surface of the skin, do not hurt or itch, sometimes they can spontaneously heal and disappear, but then reappear, often in the same place.

Sometimes the red border of the lips can become inflamed, then cheilitis spots are located on top of the reddened skin, and the redness can spread far beyond the zone where there is erosion, and the skin is thickened and swollen. The foci of cheilitis constantly appear and disappear, but the disease does not go away on its own and requires treatment, since in the places of the most persistent defects of the red border of the lips, inflammation can degenerate into a cancerous tumor.

Diagnostics of Manganotti's cheilitis and methods of therapy

It is not difficult to diagnose Manganotti's cheilitis with a visual examination of the patient. However, it should be remembered that some varieties of abrasive pre-cancer cheilitis are similar in appearance to the manifestations of herpes, pemphigus, leukoplakia, lupus erythematosus, therefore, more detailed analyzes should be performed to clarify the diagnosis.

The only absolutely effective method against Manganotti's cheilitis is surgical excision of the inflamed focus. As a rule, the patient first undergoes a course of drug therapy, which can last 1-2  month. Topical corticosteroids and, according to indications, cytostatics are used; in the presence of inflammation, antibiotic therapy may be prescribed. Vitamin A preparations are recommended inside. The patient should be warned about a categorical ban on smoking, insolation, the use of spices and other products that irritate the mucous membrane of the lips. In parallel, a complete reorganization of the oral cavity and the exclusion of factors that contribute to injury to the mucous membranes are carried out. If the examination revealed signs of cancer development,

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