Winter – a period of intense exposure to the skin of many aggressive factors: a sharp change in temperature, dry air in heated rooms, cold wind and frost.
They all lead to loss of moisture, wilting and aging of the skin. The existing age-related changes in the winter season become even more pronounced. Wishing to quickly improve their appearance, look more attractive and younger, on the eve of the holidays, patients actively turn to cosmetologists.
Fortunately for professionals and patients alike, modern injectable cosmetology offers technologies capable of rapidly improving skin quality and promoting its self-renewal. estet-portal.com will tell you more about these techniques in this article.
Mechanisms of natural self-renewal of the skin: differentiating potential
Cambial or stem cells are the fundamental source of natural regeneration and self-renewal of the skin. They are located mainly in the basal layer of the epidermis, as well as in the hypodermis.
The main function of epithelial stem cells – regeneration and renewal of the epidermis.
Each stem cell has its own differentiating potential – the ability to produce a certain number of specific mature cells.
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The prospect of using the regenerative potential of stem cells for the purpose of rejuvenation and self-renewal of tissues is the main subject of study of regenerative medicine.
How injectable cosmetic preparations can promote regeneration
The possibility of stimulating stem cells to initiate skin self-renewal processes has been of great interest for aesthetic medicine for many years.
The American company ABG Lab, which is represented in the CIS countries by Emet™, has developed the world's first cosmetic product that promotes the activation of skin self-renewal processes - Meso-Wharton P199TM (Mesowarton).
The main active ingredient of Meso-Wharton P199TM injectable is the Wharton Jelly Peptide P199 oligopeptide – artificial analog of the umbilical cord embryonic peptide.
The innovation of the development lies in the ability of this drug to influence the differentiating potential of skin stem cells.
The umbilical cord embryonic peptide is a powerful signaling factor that regulates stem cell activity.
Injection of Meso-Wharton P199TM leads to a specific effect of its active component – Wharton Jelly Peptide P199TM – and mesenchymal stem cells: the latter "receive the signal" to active differentiation and proliferation, triggering self-renewal processes.
Wharton Jelly Peptide P199 also promotes the migration of hypodermal stem cells into the dermis, followed by their differentiation into fibroblasts.
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Meso-Wharton P199 Injection TechniqueTM: A Practical Guide
The safety and efficacy of the innovative Meso-Wharton P199TM has been proven in numerous clinical studies.
Since mesenchymal stem cells are located in both the dermis and hypodermis, it is recommended to perform multi-level injection of the drug in order to achieve maximum results.
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The drug in a total volume of 1.6 ml should be injected intradermally along lines that are perpendicular to the axis of movement of the mimic muscles. For injection of the dermis, needles 31G 4 mm are used, the hypodermis – cannula 25G 50 mm.
Meso-Wharton P199TM: true skin rejuvenation and self-renewal
The result of using Meso-Wharton P199TM is true skin rejuvenation: activation of stem cells leads to the replacement of old cells with new generations, as well as the initiation of fibroblast proliferation.
A visible result can be achieved already after the first injection procedure, and all subsequent injections of the drug are potentiated by the previous ones, that is, the effect of the procedures is "accumulative".
To achieve the optimal prolonged effect, it is necessary to perform the basic course once a year: 4 procedures of intradermal administration Meso-Wharton P199TM (interval between procedures - 10 days) and 2 treatments of hypodermal injection (interval between treatments - 14 days).
Thus, Meso-Wharton P199TM (official representative - Emet ™) – it is a clinically proven rapid improvement and rejuvenation of the skin.
Thank you for staying with estet-portal.com. Read other interesting articles in the "Cosmetology" section. You may also be interested in: Injection technique for fast and effective results
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