Какие микроорганизмы вызывают тяжелые инфекции кожи и мягких тканей

 

Infections of the skin and soft tissues (SSTI), which are now interpreted in foreign literature as acute bacterial infections of the skin and skin structures, are common pathologies in clinical practice and in most cases require the use of antibiotics. The microbial spectrum of causative agents of skin infections is characterized by an increase in resistance to existing antibacterial drugs.

Find out in the article on estet-portal.com which pathogens are most often the cause of severe infectious lesions of the skin and soft tissues.

Skin infections: complexities of therapy

Treatment of patients with infections of the skin and soft tissues is additionally complicated by the presence of a number of factors that lead to severe complications and intoxication of the body (old age, obesity, diabetes and other severe concomitant diseases).

Subscribe to our page on Facebook!

Infections of the skin and soft tissues due to microbial invasion lead to inflammation of the epidermis, dermis and subcutaneous tissue with symptoms in various combinations of local hyperthermia, redness, swelling and pain.

Skin lesions in systemic lupus erythematosus

The skin is the largest organ of the body and, together with the subcutaneous soft tissues, which include layers of adipose tissue, fascia, and muscle, make up the bulk of the tissues in the human body. Typically, the skin is colonized by endogenous flora and is represented by various species of staphylococci, corynebacteria, propionibacteria and yeasts in numbers that can vary from a few hundred to several thousand per square centimeter in specific areas such as the axilla, groin and perineum .

This skin flora can act as a competitive inhibitor of pathogenic microbes.

From a clinical point of view, it is important to distinguish between those colonizations that do not require antibiotic treatment. Causes of skin and soft tissue infections

Beware of the fungus! How and why does dermatophytosis infection occur? Skin defects, such as ulcers, burns, surgical wounds, or trauma wounds, cause colonization with a wide variety of bacteria. In a number of cases of the above skin defects, these bacterial colonizations do not lead to inflammation, but sometimes, under certain circumstances, the infection can progress and become a source of proper colonization from the surrounding tissues.

 

My default image Infection can get into the tissues from the patient's skin in case of improper observance of the rules of personal hygiene, as well as the hygiene of bed linen, hands of medical personnel.

Particular difficulties arise in the treatment of patients with infections of the skin and soft tissues (trophic ulcers, bedsores, thermal skin lesions, postoperative and post-traumatic wounds)
in the presence of allergies, drug and microbial dermatitis, re-infection of wounds with hospital highly resistant strains (S aureus, S. pyogenes, Enterococcus spp., P. aeruginosa,

Enterobacteriaceae, Bacteroides spp.).

Microbial flora in skin and soft tissue infections Normally skin and soft tissue infections are caused by

several microbes at the same time, but in most cases the causative agent is Staphylococcus aureus (S. aureus). Of particular danger is the widespread strains that are resistant to most antimicrobial drugs: beta-lactam antibiotics, aminoglycosides, lincosamides, fluoroquinolones. So

S

. aureus occupies a leading position in the inflammatory process as uncomplicated and complicated infections of the skin and soft tissues.  

My default imageAn increase in infections caused by resistant strains, predominantly methicillin-resistant Staphylococcus aureus (MRSA),

is associated with significant increases in morbidity, mortality
, prolonged hospital stays, and high treatment costs.

Erythrasma: is the disease contagious and is it possible to get rid of it

In addition, gram-negative bacteria of the family Enterobacteriaceae

(

Klebsiella spp., Enterobacter spp., E.coli), which are usually resistant to beta-lactams. Knowledge of the current epidemiology and microbiological spectrum in skin and soft tissue infections are key to selecting appropriate antibiotic therapy (ABT) and optimizing treatment. When choosing antibacterial therapy, an approach is extremely important, which is determined by the level of skin and soft tissue lesions, the characteristics of the course of the disease and the presence of the phenomenon of resistance. More useful information on our 

YouTube channel:

Add a comment

captcha

RefreshRefresh