Коллаген-стимулирующие филлеры: будущий хит эстетической медицины

Collagen-stimulating fillers are becoming an increasingly popular treatment choice among patients aged 40 to 60 as they offer age-appropriate, natural and long-lasting results with a very low risk of complications.

In this article on estet-portal.com, read about how collagen stimulator treatment differs from traditional hyaluronic acid based fillers and how they can be used to contour the face, restore volume and rejuvenate the skin through tissue biostimulation.

Collagen-stimulating fillers are becoming more and more popular

In recent years, the role of volume loss in facial aging has been recognized.

The focus of treatment has shifted from working on a single local problem to a more holistic approach to rejuvenation.

Dermal fillers have become a popular treatment for volume loss and facial contour defects due to aging, disease or injury, and hyaluronic acid fillers are the most widely used. you.

Non-permanent collagen-boosting dermal fillers such as polycaprolactone, calcium hydroxyapatite and poly-L-lactic acid are becoming increasingly popular in aesthetic medicine due to the results they can achieve.

Tissue biostimulants: poly-L-lactic acid and polycaprolactone

What is the mechanism of action of collagen-stimulating fillers

When injecting any dermal filler or biostimulating agent/biomaterial, a foreign body rejection reaction always occurs in human tissue.  

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Normal healing begins within two hours of injection through an initial inflammatory phase with the formation of macrophage cells, which in turn stimulate fibroblast cells to form type III collagen or scar tissue .

This rapid production of type III collagen allows the initial healing phase to be completed quickly.

When a material such as polycaprolactone is implanted, after the initial inflammatory phase and within two weeks, the microparticles in the tissues are encapsulated by fibroblasts, resulting in fibroplasia.

This is the body's natural defense mechanism to isolate "bad" foreign particles.

This gradual process of encapsulation results in the activation of type I collagen production as long as the filler is present in the bodyme.

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What should be the ideal biostimulator

The size and shape of the biomaterial particles is a significant factor in predicting the response to the implanted material:

  • particles smaller than 20 mm are phagocytized by macrophages and excreted from the body;
  • particles from 25 to 50 mm when implanted cause the most fibrosis, and most stimulate collagen synthesis;
  • Particles larger than 50 mm are more likely to cause a prolonged inflammatory response with the formation of only type III collagen.
The ideal collagen stimulating product used in medical aesthetics should be composed of smooth microspheres no larger than 50 mm, stable in both size and shape.

Collagen-stimulating dermal fillers have a long-term effect, causing product encapsulation which, if stable, will activate type I collagen synthesis rather than an inflammatory response leading to scar tissue formation type III.

Patients are looking for natural and long-term results, and collagen-boosting fillers have become a major tool to use to achieve these goals.

Protocol for 3-Point Lifting with Fillers for Whole Face Rejuvenation

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