Daily facial care is a must for every modern woman, because it is on the skin of the face, first of all, that signs of aging appear. However, no less important is the delicate area of ​​the neck and décolleté, which can very easily give out the true age of a woman. For high-quality care and rejuvenation of the neck and décolleté area, the unique biorevitalization procedure with TM Mastelli polynucleotides is optimal.

Natalya Malichenko, a dermatovenereologist, cosmetologist, mesotherapist, specialist in anti-age medicine, spoke about the advantages of effective preparations with polynucleotides and the features of the biorevitalization procedure in an exclusive interview for estet-portal.com.

Why does the skin around the neck and décolleté require a differentiated approach?

For every woman, the appearance and condition of the skin of the neck and décolleté plays no less important role than the face. And if the neckline can be hidden under clothes, then such manipulations do not always work with the neck. Very often, it is the neck that betrays the age of a woman, because she begins to age much earlier than the skin of her face. With the slightest decrease in the level of estrogen, the skin condition of this zone deteriorates noticeably. In addition, the skin of the neck is thinner and less densely soldered to nearby tissues, which contributes to the formation of wrinkles and folds already at a young age. A smaller number of sebaceous glands in this area leads to the fact that the lipid mantle is quickly depleted and ceases to perform a protective function. In this zone, the surface network of collaterals is also poorly developed, which leads to disruption of microcirculation, and, as a result, loss of elasticity and turgor of the skin. The peculiarities of the location of the muscles and the structure of the skeletal system should not be discounted. A sedentary lifestyle, impaired posture lead to muscular-fascial imbalance, the inclusion of mechanisms for the depletion of the microcirculatory bed, spasm and the development of atrophic processes. Constitutional features and position during sleep play a huge role in the appearance of wrinkles, creases over the collarbone in the form of a "necklace", as well as in the triangle between the mammary glands. In addition, the skin around the neck and décolleté is open and exposed to solar radiation, which leads to the appearance of unaesthetic age spots and other manifestations of photoaging.  Taking into account all the features of anatomy and physiology, the cosmetologist needs to choose the best methods of correction,

Which procedures are most effective in the neck and décolleté area?

When correcting the neck and décolleté, efforts should be directed to increasing moisture, elasticity, leveling the relief and depth of wrinkles, removing age spots, improving microcirculation and tightening the skin. All these effects can be obtained by conducting a course of biorevitalization with drugs based on polynucleotides.

Biorevitalization with polynucleotides – this is an effective method of correction aimed at deep restoration of the dermis, involving the intradermal administration of preparations based on polynucleotides.

As a result of this method, repair, stimulation of the dermal matrix, synthesis of endogenous hyaluronic acid, neocollagenogenesis, neoangiogenesis, replenishment of the skin hydration level, and a powerful antioxidant effect occur. Effective preparations with polynucleotides for biorevitalization from TM Mastelli in Ukraine are represented by

company «TotisPharma Group». Since when correcting with polynucleotides, a dose of – dependent effect, there are drugs with different concentrations: PLINEST – 20 mg/ml, PLINEST FAST – 7.5 mg/ml, PLINEST BODY – 2 mg/ml, NEWEST – polynucleotides 10 mg/ml, hyaluronic acid 10 mg/ml, mannitol 20 mM/l. Protocol of procedures using Plinest products: 3-5 procedures with an interval of 1-2 weeks.<

unikalnaya-protsedura-biorevitalizatsii-polinukleotidami-dlya-omolozheniya-oblasti-shei-i-dekolteWhat results can be achieved with biorevitalization of the neck and décolleté area with TM Mastelli polynucleotides?

As a result of the course of biorevitalization of the neck and décolleté area, polynucleotides restore water balance and create ideal conditions for cell activity, restart renewal processes, eliminate the effects of stress and adverse environmental effects, naturally restoring youth and health to the skin. It's a healthy skin treatment from the inside out! Visually, we will see skin tightening, reduction of wrinkles and folds, pronounced lifting, smoothing of skin tone and relief. The biorevitalization procedure is used both for prevention and correction of age-related skin changes in the neck and décolleté. The method is effective and allows you to achieve the desired results without any risks.

Why do we prefer preparations based on TM Mastelli polynucleotides for work in the neck and décolleté area?

Because these drugs are proven effective, which is very important! The stimulating effect of polynucleotides on the dermal matrix is ​​much greater than that of biorevitalization preparations with hyaluronic acid, which are traditionally used. In addition, hyaluronic acid, as you know, strongly attracts water, "weighting" the body. skin, and the anatomical features of the decollete and, especially, the neck are such that it is unfavorable!

unikalnaya-protsedura-biorevitalizatsii-polinukleotidami-dlya-omolozheniya-oblasti-shei-i-dekolteWhich clinical studies confirm the high effectiveness of polynucleotides when working in the neck and décolleté area?

Italian pharmaceutical company Mastelli (

represented in Ukraine by «TotisPharma Group»

), founded in 1952 in San Remo, manufactures drugs for dermatology and gynecology, medical equipment and cosmetics.

Mastelli pays attention to the most important aspects in the production of products, namely the high quality of the products, safety and, most importantly, proven effectiveness.

To do this, the company conducts a lot of clinical research, collaborating with leading medical universities. For example, some of them were carried out at the Faculty of Clinical and Experimental Medicine of the University of Parma, under the guidance of Professor Stefano Guizzardi. TM Mastelli were pioneers in the production of polynucleotides. More than 40 years of experience in research and application of low molecular weight DNA has allowed the company to develop an ideal range of products for biorevitalization and prove their effectiveness and safety. Biorevitalization procedures with preparations based on polynucleotides can prevent wilting and effectively slow down the aging process of the neck and décolleté area, which is expressed in increasing skin tone and turgor, improving its color and reducing the severity of wrinkles.

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