Seize the Moment: Treat DIC as Early as Possible

Disseminated intravascular coagulation, or DIC, can be extremely dangerous, as it can develop at lightning speed, causing severe internal bleeding - massive and unstoppable. It is very important to timely identify patients at risk of developing this disease, especially among pregnant women, since early treatment of DIC, taking into account the form of the process and the depth of the lesion, can prevent deep damage to blood vessels and pathology of internal organs.

What signs will indicate the development of DIC

Symptomatology of DIC depends on the form of development of the disease and its stage, & nbsp; from the signs of the disease superimposed on it, which provoked the development of DIC, from the prevalence of damage to all organs and the state of the body as a whole, its compensatory mechanisms.

Forms of the disease and their signs that are important in the treatment of DIC

Forms of DIC syndromes are usually determined by the stage of the course of the pathological process and the nature of its manifestation. The following forms of manifestation of DIC syndrome are distinguished:

• sharp manifest – a state of shock develops in a few hours with signs of pulmonary edema, hypotension, loss of consciousness, increasing bleeding, massive bleeding (nasal, pulmonary, uterine, gastric);
• acute fulminant – develops within a few minutes coagulopathy, turning into cardiopulmonary and hemorrhagic shock;
• subacute – has a local course, manifested by moderate hemosyndrome, pale marbling of the skin, numerous petechiae, bleeding of mucous membranes;
• chronic – manifestations of hemorrhagic diathesis are increasing, the functions of internal organs are gradually disturbed
• Treatment of DIC syndrome should be started taking into account the fact that a purulent infection can join, and wound healing is often accompanied by the formation of keloid scars.

DIC treatment, diagnosis and prognosis

Diagnosis of DIC syndrome will help, in addition to a thorough history taking and examination of the patient, analysis of laboratory data. The task of diagnostic measures in the case of DIC is, first of all, to search for the etiological factor that provokes the disease, as well as to determine the stage of coagulopathy, clarify the nature of bleeding and the depth of already occurring disorders.

The sooner the treatment of DIC is started, the greater the chances of success. If we are talking about an asymptomatic course of the disease, the main attention is paid to the treatment of background pathology. At the same time, deviations in hemodynamic parameters are corrected and, if possible, violations that have already occurred in the work of internal organs are eliminated. Recommended nootropic drugs, angioprotectors.

Treatment of DIC in its chronic stage involves the use of vasodilators, antiplatelet agents. Skin hemorrhages are treated with dicynone dressings, if necessary, corticosteroids are prescribed, and plasmapheresis is recommended.

In acute DIC, it is necessary, firstly, to urgently eliminate the root cause of its development (for example, to carry out emergency delivery) and begin the administration of anticoagulants, fibrinolytics, antiplatelet agents in order to eliminate hypercoagulability. The therapy is carried out under careful dynamic hemocontrol. If life-threatening bleeding develops, protease inhibitors, aminocaproic acid, other antifibrinolytic agents are prescribed according to indications, measures are taken & nbsp; to eliminate organ failure. The prognosis for the acute form of DIC is not very good, since there is a possibility of intractable massive blood loss, shock, acute respiratory or renal failure.

Thus, a positive prognosis in the treatment of DIC directly depends on how early treatment was started. At the same time, it is very important to identify in advance patients from risk groups (especially among pregnant women), to control the underlying disease that can cause DIC syndrome.