Почему может возникать гранулема после инъекций филлеров

Facial contouring with injection of fillers – It is one of the most popular and sought after cosmetic procedures today. With the help of the introduction of fillers, it is possible to correct facial features, fill in missing volumes and, to a large extent, improve the appearance of a person.

But it is this cosmetic procedure that is often accompanied by complications, among which there is a foreign body granuloma. Today on estet-portal.com read why granuloma can occur after filler injections, and what therapeutic methods will help to effectively eliminate this problem.

Why forms granuloma after injection of fillers

Injection Facial Fillers – This is a procedure accompanied by the introduction of a foreign body into the patient's body. And it happens that the body recognizes this foreign body and tries to protect itself from it.

The formation of granuloma after filler injections is a protective reaction, which is an inflammation resulting from the transformation and proliferation of cells capable of phagocytosis.

The function of such a reaction is to isolate and prevent the migration of foreign bodies by encapsulating them, consisting of macrophages and monocytes.  This complication occurs quite rarely: pathology is recorded in only 0.01-1% of cases, however, aestheticians should know how to deal with this problem.

Granuloma after filler injections:

  • causes of granuloma formation after filler injections;
  • clinical picture of foreign body granuloma;
  • treatment methods for granuloma after filler injections.

Among the main factors affecting the risk of granuloma formation after filler injections are:

  • introduction of an unreasonably large amount of filler;
  • intramuscular filler injection;
  • aliquatic properties of the drug;
  • previous trauma or infection in the area of ​​correction.

Read also: "Detailed classification of dermal fillers in cosmetology"

In addition, the shape of the filler microspheres plays a certain role in the development of the pathological process: as it turned out, after the implantation of microspheres with a smooth surface, a foreign body granuloma occurs much less frequently than after the introduction of a filler whose particles have sharp edges. At the same time, the biodegradable properties of the filler do not affect the incidence of granulomas.

Clinical picture of foreign body granuloma

 

granulema-posle-in-ektsij-fillerov-prichiny-i-metody-korrektsii

 

The clinical picture in the event of a foreign body granuloma is quite characteristic: on the patient's skin, at the injection site, red papules, nodules or plaques are formed, which may be with or without ulceration. Over time, these elements may become harder, which is associated with fibrosis.

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A granuloma after filler injections does not occur immediately: the development of the clinical picture is preceded by a latent period, the duration of which can range from several months to several years after the injection of the drug. 

Read also: Swollen cervical lymph nodes: correct diagnosis

Characteristically, culture results of granulomatous elements in will always be negative.

Methods of treating granuloma after filler injections

Treatment of granuloma after filler injections can be conservative or, in particularly difficult cases, surgical. At the initial stages of therapy, the patient undergoes intralesional administration of glucocorticosteroid drugs. If a granulomatous reaction develops after an injection of hyaluronic filler – hyaluronidasey can be used at the beginning of treatment. If the patient does not respond to such therapy – 5-fluorouracil is added to the treatment regimen, which has the ability to suppress the activity of fibroblasts, reducing the processes of fibrosis in tissues.

If there is no response to treatment with glucocorticosteroids and antimetabolites – the patient is recommended surgical excision of the granulomatous element.

You may also be interested in: «Nodules after filler injections: causes, treatment and prevention».

In order to prevent the occurrence of granuloma after filler injections, it is necessary to avoid factors that provoke this complication. 

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