The issue of aesthetic procedures still remains open due to insufficiently deep research into their impact on the fetus. New drugs and techniques are very rarely tested on pregnant women due to the risks to the mother and fetus, which makes it difficult to obtain objective data on their effects.
But specialists keep this aspect of aesthetic medicine in focus and try to study the issue of safety as much as possible. Previously, estet-portal.com published the first part of the article, which reviewed the US FDA drug safety classification and the latest data regarding the use of dermal fillers and chemical peels during pregnancy. In this publication, we will analyze the impact of other popular aesthetic procedures and anesthetics.
Lasers during pregnancy — increased risk of hyperpigmentation
Lasers are used for a variety of aesthetic procedures, but to the best of our knowledge, they have not been tested for safety in pregnancy.
The lack of data regarding these aesthetic procedures means that it is advisable to abstain from them during pregnancy. When performing procedures with a laser, there is always a risk of such a side effect as hyperpigmentation, but during pregnancy they increase significantly.
However, there have been a number of studies evaluating their safety in treatment during pregnancy, such as for kidney stones, purulent or genital warts.
Injectable anesthetics: lidocaine, bupivacaine and mepivacaine
Lidocaine – a popular local anesthetic injection and is used in the administration of botulinum toxin and dermal fillers. It is classified as a pregnancy category B drug. Classification The FDA has been published in the first part of the article. Once in the bloodstream, lidocaine can cross the placenta and enter the fetal circulation.
In 2015, a study was conducted that showed an increase in the number of adverse effects from the use of lidocaine in 210 women for dental procedures. Thus, a slight increase in miscarriages, congenital anomalies, and medical/surgical complications was found. But when conducting experiments on rats,
The main risks of lidocaine administration are associated with high exposure or accidental arterial injection, which could theoretically lead to damage to the fetal cardiac or central nervous system.
However, the maximum safe injection dose of lidocaine is 4.5 mg/kg or 300 mg, which is significantly lower than the dose used in aesthetic procedures. Large doses are toxic to the pregnant woman and may cause symptoms such as tachycardia, dizziness, restlessness and headache.
Other local anesthetic injectables such as bupivacaine and mepivacaine are classified as Category C drugs and should therefore be avoided as there are safer alternatives such as lidocaine.
Studies have shown that the use of mepivacaine causes complications such as: fetal bradycardia, preterm labor and a two-fold increase in the risk of congenital anomalies.
Local anesthetics: choosing the lesser of two evils
Lidocaine is a popular local anesthetic but is often used in combination with prilocaine because it provides superior analgesia. The mixture is classified as category B during pregnancy, but increased risks are present due to the inclusion of prilocaine. So, studies have shown: when using this drug during pregnancy, the fetus may develop methemoglobinemia.
Benzocaine and tetracaine are classified as Category C due to active penetration through the skin. Given this fact, lidocaine and prilocaine mixture is the preferred choice of local anesthetic if needed during pregnancy.
Please note that the effectiveness of anesthetics increases with occlusion, and with it, the percentage of penetration into the systemic circulation also increases. Therefore, when using these drugs during pregnancy, occlusion should be avoided to minimize the risks of adverse effects.
Botulinum toxin: questionable safety
Botulinum toxin – one of the most popular means in aesthetic cosmetology, but it is also used for other purposes, for example, for hyperhidrosis. Botulinum toxin is officially a category C drug, and pregnancy is a contraindication to its use according to the manufacturer's recommendations.
There is some evidence that botulinum toxin is safe to use during pregnancy, but experts still insist that there is not enough data to date to confirm the absolute safety of this substance.
However, several studies have been conducted studies that analyze the effects of medically indicated use of botulinum toxin during pregnancy. Despite the use of a higher dose of the substance for medical purposes, a significant increase in risks to the fetus was not observed. Theoretically, if the injection is performed correctly, botulinum toxin is unlikely to enter the systemic circulation.
The size of the botulinum toxin molecules is quite large, so the likelihood that they can cross the placental barrier – very small. Aesthetic procedures are carried out using a much lower dose of the drug than the expected dangerous concentration (100 units versus 600 units).
The case for the safety of botulinum toxin during pregnancy is compelling, but once again we would like to point out that there is not yet enough data to confirm absolute safety.
no significant increase in risk to the fetus was observed. Theoretically, if the injection is performed correctly, botulinum toxin is unlikely to enter the systemic circulation.
The size of the botulinum toxin molecules is quite large, so the likelihood that they can cross the placental barrier – very small. Aesthetic procedures are carried out using a much lower dose of the drug than the expected dangerous concentration (100 units versus 600 units).
The case for the safety of botulinum toxin during pregnancy is compelling, but once again we would like to point out that there is not yet enough data to confirm absolute safety.
no significant increase in risk to the fetus was observed. Theoretically, if the injection is performed correctly, botulinum toxin is unlikely to enter the systemic circulation.
botulinum toxin is unlikely to enter the systemic circulation.
The size of the botulinum toxin molecules is quite large, so the likelihood that they can cross the placental barrier – very small. Aesthetic procedures are carried out using a much lower dose of the drug than the expected dangerous concentration (100 units versus 600 units).
The case for the safety of botulinum toxin during pregnancy is compelling, but once again we would like to point out that there is not yet enough data to confirm absolute safety.
botulinum toxin is unlikely to enter the systemic circulation.
The size of the botulinum toxin molecules is quite large, so the likelihood that they can cross the placental barrier – very small. Aesthetic procedures are carried out using a much lower dose of the drug than the expected dangerous concentration (100 units versus 600 units).
The case for the safety of botulinum toxin during pregnancy is compelling, but once again we would like to point out that there is not yet enough data to confirm absolute safety.
Aesthetic procedures are carried out using a much lower dose of the drug than the expected dangerous concentration (100 units versus 600 units).
The case for the safety of botulinum toxin during pregnancy is compelling, but once again we would like to point out that there is not yet enough data to confirm absolute safety.
Aesthetic procedures are carried out using a much lower dose of the drug than the expected dangerous concentration (100 units versus 600 units).
The case for the safety of botulinum toxin during pregnancy is compelling, but once again we would like to point out that there is not yet enough data to confirm absolute safety. Simpler aesthetic procedures: safety under control
It has been proven that other simple aesthetic procedures, including the removal of benign neoplasms using cryotherapy, electrocoagulation and others — safe during pregnancy. Of course, there is a risk of bleeding or incomplete removal of the formation, but they are insignificant. Some procedures may require a local anesthetic (described above), but most of them can be performed without anesthesia. physiological changes during pregnancy. Minor aesthetic procedures like cryotherapy, electrocautery, mechanical hair removal are considered safe during pregnancy. Some researchers claim that chemical peel — safe, but excessive systemic infiltration has been shown to cause side effects in both animals and humans.Anaesthetics, the most common of which is lidocaine, should also be used with caution during pregnancy. It has been proven to be the safest of the injectable and topical anesthetics for use during pregnancy. For injectable procedures such as botulinum toxin injections and dermal fillers, there has not been enough research to date assessing their safety. The question of the safety of most aesthetic procedures during pregnancy remains open today. Many of them carry an increased risk of complications and side effects. It should also be remembered that the wound healing process changes during pregnancy, and this may lead to a deterioration in the aesthetic results for the patient.Given all the above arguments, a conscientious doctor should not only inform the patient about the possible risks and suggest postponing aesthetic procedures during pregnancy. Adapted from Aestheticsjournal.com that during pregnancy the wound healing process changes, and this may lead to a deterioration in the aesthetic results for the patient.Given all the above arguments, a conscientious doctor should not only inform the patient about the possible risks and offer to postpone the aesthetic procedures for a while pregnancy. Adapted from Aestheticsjournal.com that during pregnancy the wound healing process changes, and this may lead to a deterioration in the aesthetic results for the patient.Given all the above arguments, a conscientious doctor should not only inform the patient about the possible risks and offer to postpone the aesthetic procedures for a while pregnancy. Adapted from Aestheticsjournal.com See also: Effective treatments for gestational diabetesShare:
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