Erysipelas: who develops it most often and why

One of the most urgent problems of modern medicine is the widespread occurrence of chronic diseases that can significantly impair the quality of life and require long-term expensive treatment. That is why today much attention is paid to the timely diagnosis and prevention of these pathological conditions, because the sooner the disease is recognized and appropriate treatment is prescribed, the more likely success is. In the structure of all chronic diseases, a special place belongs to infectious diseases due to their tendency to a recurrent course and the development of complications. Such pathological conditions include erysipelas – the most common infectious disease with a contact mechanism of transmission. Read more about risk factors and mechanisms for the development of erysipelas on the estet-portal.

What is known about the etiology of erysipelas

The causative agent of erysipelas is group B beta-hemolytic streptococcus, which lives on the skin and mucous membranes of the human body, and is capable of producing a large number of enzymes:

hyaluronidase, streptokinase, deoxyribonuclease and many other toxigenic factors.

This microorganism is the etiological cause of the development of many chronic diseases, it is often identified in clinically healthy people – carriers of hemolytic streptococcus.

The latter, due to the subclinical course of the pathological process, play a key role in the spread of infectious diseases among the population.

Erysipelas:•    What pathological conditions contribute to the development of erysipelas;
•    Mechanism of implementation of erysipelas and the role of the macroorganism in it.

See also:

Redness of the nose can be a symptom of erysipelas

What pathological conditions contribute to the development of erysipelas

Although streptococcal infection is ubiquitous – ubiquitous throughout the world, not all carriers of streptococcus develop erysipelas.

This phenomenon indicates that this pathological condition is realized against the background of predisposing factors, which include the following:

1.    Hereditary predisposition;

2.    Decrease in the overall immunological resistance of the body against the background of concomitant diseases (diabetes mellitus, chronic kidney disease, atherosclerosis, alcoholism), the period of convalescence, chemotherapy, X-ray therapy for autoimmune and oncological pathologies;

3.    Decrease in local immunological resistance in people whose work is associated with physical exertion and is accompanied by constant microtraumatization (builders, plumbers, electricians, athletes and others) or against the background of

dermatitis, dermatosis, vascular insufficiency with impaired skin trophism ;

When hemolytic streptococcus enters the damaged skin from the external environment or by endogenous infection from the foci of persistence of the pathogen against the background of the above predisposing factors, the process of erysipelas develops.

The mechanism of erysipelas and the role of the macroorganism in it

After getting group A beta-hemolytic streptococcus on the skin and in the underlying histological structures, it penetrates into the system of local lymphatic capillaries. The causative agent, multiplying, produces a large amount of toxins that contribute to the development of the clinical picture of the disease and lead to lymphostasis.

The central link in the pathogenesis of erysipelas is the primary sensitization of the macroorganism to streptococcal infection, which leads to the development of a hyperergic immune response and the formation of immune complexes.

That is why

erysipelas is an infectious-allergic disease, and the state of the macroorganism plays the same role in its development as the etiological pathogen. This must be taken into account when drawing up a treatment regimen for erysipelas: the treatment of erysipelas should consist of both etiotropic therapy and the correction of concomitant pathological conditions, such as lymphostasis, venous insufficiency, diabetes mellitus, and others.

If necessary, the physician should refer the patient to an appropriate specialist to correct underlying disease and prevent future erysipelas. Thank you for staying with estet-portal.com, read other interesting articles in the section

«Dermatology».