The topic of cellulite correction and local fat deposits has been relevant for a long time - from the end of the 20th century to the beginning of the 21st century. Modern fashion trends, fortunately, are already moving away from the pretentious image of the eternal anorexic girl. But even in the situation of modeling the recently popular "Brazilian ass"; we, nevertheless, clearly understand that despite the desire to achieve certain, rather magnificent forms, the patient is absolutely not interested in having an “orange peel”, because the times of chanting “pretty dimples” irretrievably sunk into oblivion. Some questions from readers of estet-portal.com about how to correct unwanted fat deposits and manifestations of cellulite were answered by a dermatocosmetologist, ANC trainer in contour correction,
Why is it important to know the principle of fat formation for cellulite correctionWhen analyzing the possibilities of correcting cellulite and local fat deposits, we must rely on knowledge of the pathogenetic processes that lead to these problems. At the heart of adipose tissue is the adipocyte as an adult, formed cell, surrounded by an extracellular matrix. The fat cell is formed as a result of the process of mesenchymal differentiation, and according to the latest data – and hematopoietic stem cells. In the course of life, the adipocyte differentiates. Gradually, all vacuoles filled with triglycerides merge into one large vacuole, which displaces the nucleus almost to the cell membrane. The more crowded the cell is, the less functional activity is shown by the cellular apparatus responsible for energy metabolism: mitochondria and the Golgi complex. Over time, in each individual cell, a vicious circle of blocking the exchange of fats can be created.
There are two types of subcutaneous fat (SAT).
• First type. It includes functional adipose tissue, evenly distributed throughout the body and creating the main volumes and excess weight. Sports, diets and stress primarily affect it, significantly reducing the amount of body fat.
• Second type. It includes reserve adipose tissue. It is located locally, in certain places, thereby distorting the contours of the body. Reserve adipose tissue is almost insensitive to the main factors of weight loss — diets, exercise. Zones of accumulation of adipose tissue of the second type in both women and men are often due to the action of sex hormones, genetic predisposition.
An increase in the number of cells leads to an increase in appetite, since each new cell requires energy. "Broken" the mechanism of energy metabolism provokes instant accumulation of fats. And, as a result, the formation of a "vicious circle" takes extremely little time.
How cellulite is formed and why it is necessary to take into account its stages when planning a correction
The formation of cellulite and hypertrophy of localized fat deposits (LFA) are based on essentially very similar processes. For cellulite, the reaction of the connective tissue is of great importance. Strengthening of fibrous constrictions due to violation of trophism by pinched vessels, puffiness – all this leads to the development of each subsequent stage of cellulite.
1. Stage of initial edema. It has practically no visible clinical manifestation. The patient usually feels "a little swollen" and usually associates this with PMS. It is characterized by an initial lesion of the lymphatic vessels. As a rule, diet, massage, etc. are extremely effective at this stage.
2. Stage of pronounced edema. It is characterized by persistent persistent dense edema, blanching and reduced tissue temperature. At this stage, the defeat of the venous system begins. Diets, massage, lymphatic drainage hardware techniques will still be effective.
3. Micronodular stage. Persistent edema leads to the formation of "capsular syndrome" when the body begins to build fibrous capsules – honeycomb, around areas with congestion. There is a lesion of the bloodstream at the level of arterioles. Pinch Syndrome is also negative (the patient feels pain when pinched).
4. Macronodular stage – large "dimples" are preserved in any position, without squeezing the tissues. Pinch Syndrome nbsp; - positive (the patient does not experience pain), respectively, we can talk about damage to the nervous system.
As we understand, each of these stages requires its own correction algorithm.
Leaving aside surgical correction, let's focus on injection techniques, which are much more widespread and enjoy considerable popularity. Patients usually turn to us at the micronodular and macronodular stages of cellulite.
• direct lipolytic in the first stage,
• indirect lipolytic in the second stage,
• lifting products at the third stage.
This technique is called Network lipolysis and has remained relevant over the past years. Another technique, in my opinion, more preferable, involves the simultaneous introduction:
• direct lipolytics in areas of depression caused by fibrous retraction,
• a cocktail that stimulates lymphatic drainage, containing antioxidants and indirect lipolytics, into areas of persistent edema (the so-called "+zones").
At the next stage, the principle of tissue lifting is preserved.
How do you feel about the use of direct lipolytics in the correction of body fat
Direct lipolytics, which include drugs deoxycholate and phosphatidylcholine, work on the principle of destruction of the fat cell membrane and subsequent emulsification of fats.
A few years ago there was talk of banning direct lipolytics due to the high traumatization of tissues during their introduction and a fairly high level of overall negative impact on the body. However, after Kybella's direct lipolytic received FDA approval in the USA, it became clear that effective drugs should not be abandoned. Simply, like all products in medicine, they should be used by trained professionals, according to the method shown in patients with no contraindications.
In my practice, I use an ex temporo cocktail consisting of 10 ml of Dermastabilon (phosphatidylcholine 50 mg/ml, deoxycholate 20 50 mg/ml) and 10 ml (2 ampoules) of RRS Silisorg (organic silicon) presented on in our market
by the company «ANK».
Sodium Deoxycholate – salt of deoxycholic acid, formed in the liver when deoxycholic acid binds to an amino acid. Deoxycholic acid and sodium deoxycholate are amphiphilic compounds and have detergent properties. They emulsify fats to form micelles, while sodium deoxycholate is more active.
In 2008, a double-blind, randomized study was conducted, which showed fewer ecchymosis, indurations and pain in patients with the introduction of a solution of phosphatidylcholine/sodium deoxycholate compared with mono-administration of deoxycholate.
The simultaneous use of phosphatidylcholine and deoxycholate increases the effectiveness of the procedure by 35%. According to numerous clinical studies (Dermastabilon), the addition of a bioavailable silicon solution to the preparation, on the recommendation of F. Depre and E. Ranneva, reduces the risk of complications by more than 50%,
How to use direct lipolytics to prevent unpleasant side effects
A lipolytic cocktail is administered classically: we pinch the volume of fat to be corrected with our thumb and forefinger and inject the drug, making sure that it does not enter the muscle tissue in any case.
What drugs do you use to correct body fat
• normalize blood circulation;
• stabilize and reduce the size of adipocytes;• pause if possible differentiation of mesenchymal cells into adipocytes.
For all three directions I use RRS HA Cellutrix, a powerful lipolytic and anti-oxidant, vascular and lymphatic drainage drug. The composition of the drug, which is based on non-stabilized HA of non-animal origin (Japan) and a patented biorevitalization solution, includes:
• pharmacopoeial dosages of antioxidants (vit. C, dehydrotriferullic acid, hederacoside E and F, etc.),
• flavonoids (cinarathrioside, quercetin, kaempferol, troxerutin, rutin, hesperidin),
• trace elements (I, K, Br, Cl, Ca, Fe, Si, Mg),
• vitamins (vit. C, vit. A, vit. B2),
• saponins (ruscogenin, neuroscogenin, α-hederin, hederasaponin C, asiaticoside, etc.),
• triterpenes (Asian additive, madecassonic acid, succinic acid),
• amino acids (L-carnitine),
• ά-hydroxy acids (hydroxysuccinic acid, lactic acid),
• polyphenols (chlorogenic acid, phloroglucinol).
• triterpenes (Asian additive, madecassonic acid, succinic acid),
• amino acids (L-carnitine),
• polyphenols (chlorogenic acid, phloroglucinol).
• triterpenes (Asian additive, madecassonic acid, succinic acid),
• amino acids (L-carnitine),• ά-hydroxy acids (hydroxysuccinic acid, lactic acid),
• polyphenols (chlorogenic acid, phloroglucinol).There is a lot of talk about the cellular activating action of fucoxanthin now - a pigment obtained from brown algae. Unfortunately, there are no significant European studies on this topic, however, it is recognized as a fairly effective ingredient that enhances the overall effect of lipolytic drug formulas.
Many drugs contain unexplored ingredients. Especially often we encounter such a situation when dealing with mesopreparations based on peptides. In Europe, literally single formulas were approved, the rest were recognized as not fully understood. Some large companies have even lost the CE certificate for their products due to the use of such "non-medical" products in their formulations. peptides.
Which injection technique is better to choose for the correction of cellulite and local fat deposits
A separate stage of correction, following the effect of lipolytics, is to increase skin elasticity. For these purposes, the use of preparations from
ANK company, combining hyaluronic acid, bioavailable silicon and DMAE, is ideal.
Thus, in my practice I usually use the following algorithm.
1. Simultaneous correction with direct and indirect lipolytics - 4-7 procedures, interval 1 time per week, the number of procedures varies according to indications. If there are no "-zones", then I use only RRS HA Cellutrix.
2. Correction of skin elasticity and tone (RRS Silisorg Tensor/ RRS HA Strimatrix) – 3-4 procedures 1 time per week.
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