Succinate: the secret ingredient of rejuvenation

Prior to 2004, the SUCNR1 receptor was classified as an "orphan" receptor, until a landmark study (Weihai He at. o.) paired it with succinate. The specificity of the receptor for

is uniquely high (as compared with more than 800 substances). And since these receptors are contained in different tissues, the interaction of succinate with them allows you to achieve

. This topic for the readers of

-portal.com was deeply revealed by a plastic surgeon, a specialist in injection cosmetology, certified trainer of the company Hyalual, Alexander Karpinsky.

• Interaction of succinate with SUCNR1 receptors in various skin structures
• Practical case: Full-face correction with succinate preparationm
Interaction of succinate with SUCNR1 receptors in various skin structures

The introduction of a succinate-containing drug

by the company Hyalual has a complex rejuvenating effect due to the interaction of succinate and SUCNR1 receptors:

fibroblasts
• allows to stimulate the synthesis of collagen and its own HA, contributing to rapid tissue regeneration. The presence of SUCNR1 receptors on
macrophages
• allows you to fundamentally influence the processes of skin regeneration and repair. Localization of SUCNR1 on
keratinocytes
• allows for effective use of topical succinate-containing products (Profi Delux, Daily Delux). Presence of receptors on
hair follicles
• allows to improve hair growth and quality, makes it possible to combat alopecia.

of Succinate-Containing Company Hyalual Activity in Skin:

• vascular wall remodeling;
• physiological stimulation of the production of endogenous growth factors
• a. 

Telegram! Practical case: Full-face correction with a succinate-containing preparation

fat compartments hypertrophy with age – increase in volume. But

fat pads can lose volume. Increasing the volume of deep fat compartments provides support to the overlying facial structures, and gives a pronounced lifting effect.

Protocol for the procedure for correcting age-related changes in the face

:

correction area

– Full Face;

1. Product – H&S;
2. volume of product used - 5 ml;
3. method of insertion - cannula 22G;
4. technique of introduction - linear-retrograde, fan-shaped;
5. depth of reference - deep fat pads;
6. course: 3 treatments, 3 weeks apart.
7. A drug for correction of age-related changes in delicate areas of
sensitive skin in order to reduce the risk of swelling and trauma to the patient.

Composition:

High molecular weight hyaluronic acid – 0.9%

Succinic acid (sodium succinate) – 1.6%

The physiological concentration of
2. hyaluronic acid 0.9%
and optimal viscoelastic properties provide natural dermal repair and an easy way to administer the drug, minimizing the risk of injury to sensitive skin.

 

H&S

redermalization has a fast therapeutic effect, improving the quality of sensitive skin.

Thus, the correction of deep fat pads allows you to achieve pronounced results rejuvenation

in the shortest possible time. 

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