The safe and effective use of botulinum toxin depends on proper storage of the product, selection of the correct dosage, and correct methods of reconstitution and administration.
Physicians working with neurotoxin must understand the relevant neuromuscular and structural anatomy of the area and must always take a detailed history of the patient.
The recovery procedure is often confusing for specialists, however, there is nothing difficult in it if you follow the instructions of the drug. About how to restore botulinum toxin correctly, told estet-portal.com dermatovenereologist, cosmetologist of the clinic of aesthetic medicine "Beautycom" (Vinnitsa) Ekaterina Zatserkovna.
Dose selection for botulinum toxin recovery
The restoration of botulinum toxin preparations is of great importance for obtaining the required qualitative result. Also, the correct restoration of botulinum toxin – this is a guarantee of the safety of botulinum therapy, and therefore it is important to follow certain rules when working with neuroprotein.
First, it is important to understand that units of botulinum toxin of one drug are not related in any way to units of another. The doses used for the drug BOTOX® of the Allergan company differ from those recommended for work with other neurotoxins, therefore, when working with this agent, you must be guided medical instructions only!
Secondly, doses for elderly patients are similar to those for young adults, however, the doctor may decide to administer the lowest effective dose for maximum patient safety.
When starting treatment, use the lowest recommended dose. When treating adult patients for one or more indications, the maximum cumulative dose should not exceed 400 units at intervals of 3 months.
Use of high doses of botulinum toxin in the correction of glabellar wrinkles
What is the recommendation for restoring BOTOX®
BOTOX® can only be dissolved with sterile saline (0.9% sodium chloride solution). The required amount of solvent is drawn up with a syringe and injected into the rubber cap of the botulinum toxin bottle pretreated with alcohol.
The reconstituted product must be clear, colorless and free of particulate matter.
Another important point of working with botulinum toxin – you should always pay attention to the volume of the bottle of the BOTOX®, because the amount of solvent to reconstitute the corresponding number of units of the drug is different for the BOTOX® 100 units and 200 units.
Therefore, the amount of 0.9% sodium chloride solution to restore is calculated, respectively, per 0.1 ml of the drug.
BOTOX Recovery Chart®:
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BOTOX storage® after reconstitution
This rule is often neglected by many specialists, since the price of the drug is quite high, and there can be quite a lot of it left after the procedure. However, the medical instructions for the drug indicate that after reconstitution, it can be stored for no more than 24 hours.
After reconstitution, the drug can be stored no longer than a day.
BOTOX® can only be handled by a qualified physician who has undergone the necessary training, since the dose and number of injections of the drug into one muscle are not defined, therefore it is the physician who decides on the individual therapeutic dose.
Original products of Allergan You can only purchase from the official distributor.
World-wide research: higher doses of BOTOX®
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