Possibilities of using polynucleotides to stimulate the growth of eyebrows and eyelashes

Patients of cosmetologists often complain about the unsatisfactory condition of the periorbital zone. The unique anatomy and exceptional delicacy and sensitivity of the skin around the eyes make it the most vulnerable to aging processes. These processes can be prevented and reversed with the help of PDRN, which stimulate cellular self-healing and act safely, but at the same time very effectively.

Mastelli polynucleotides from the official distributor TOTISPHARMA GROUP are also intended for stimulation  growth of eyebrows and eyelashes. In the article estet-portal.com we will talk about the key mechanisms of PDRN in the periorbital zone and focus on the protocols for working with eyebrows and eyelashes. <

• What age-related changes occur in the periorbital zone
• Mechanism of action of Mastelli polynucleotides in the area around the eyes
• Plinest products for periorbital rejuvenation
• Plinest Fast Polynucleotides for Growth Stimulation of eyebrows and eyelashes

What age-related changes occur in the periorbital zone

The skin around the eyes is the first to react to the processes of chronoaging and the impact of negative environmental factors, since it is initially thin and practically devoid of sebaceous glands.

 

At about 25 years of age, the level of growth hormone, which stimulates the growth and renewal of cells, decreases. As a result, the ability of fibroblasts to regenerate and synthesize elements of the extracellular matrix is ​​reduced.

 

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With age, in the area around the eyes occurs: 

• slow cell renewal;

 

• deterioration in the ability to retain moisture;

 

• decrease in the number of glycosaminoglycans (HA, etc.);

 

• displacement of fat pads;

 

• decrease in tone and elasticity of the vascular wall;

 

• lipofuscin deposition;

 

• resorption of bone structures.

 

The first layer in which age-related changes occur, – leather. In order to prevent their appearance or eliminate already visible signs of aging,

it is necessary to act on two levels: 

• epidermis (home care is aimed at this, which supports the function of the epidermal barrier, thereby preventing moisture loss and eliminating dry skin around the eyes);

 

• dermis (injection techniques are used for this, in particular, revitalization with polynucleotides, which stimulates fibroblasts, angiogenesis, and relieves inflammation, provides excellent results).

 

To the company's portfolio

  TOTISPHARMA GROUP includes Plinest (Mastelli) products based on PDRN, which are ideal for revitalizing the area around the eyes, starting from 25 years.  

Mechanism of action of Mastelli polynucleotides in the area around the eyes

The effectiveness of revitalizing therapy with Plinest (Mastelli) polynucleotides is due to the simultaneous action in several directions at once:

 

• cell link;

 

• vascular link;

 

• stimulation of HA synthesis;

 

• stimulation of collagen synthesis.

 

 

 

Mastelli polynucleotides do not cause puffiness in the area around the eyes and at the same time stimulate:

 

• fibroblast growth;

 

• vascular endothelial growth factor (VEGF);

 

• collagen synthesis;

 

• tissue oxygenation;

 

• synthesis of fibronectin.

 

As a result of increased angiogenesis and strengthening of the walls of blood vessels, the supply of oxygen and nutrients to skin cells improves. Stimulation of fibroblasts leads to increased synthesis of collagen, elastin and other elements of the extracellular matrix. Result – radiance, hydration, smoothing of the relief and increase of turgor and elasticity of the skin.

One of the key benefits of Plinest – high bioavailability (90%).

 

In addition, PDRN: 

• reduce the amount of pro-inflammatory and increase the amount of anti-inflammatory cytokines;

 

• improve the antioxidant system;

 

• normalize biochemical processes in cells;

 

• improve the outflow of decay products through the lymphatic vessels;

 

• enhance the process of reutilization, elimination of cellular damage

and mutations. 

Plinest preparations for rejuvenation of the periorbital zone

The Plinest PDRN line from the leading Italian brand Mastelli includes two preparations for working with the periorbital zone.

 

1. Plinest Fast – polydeoxyribonucleotides 7.5 mg/ml 

 

 

The preparation is a liquid gel for intradermal administration of a long-chain polynucleotide, which:

 

• fully biocompatible with tissues;

 

• absolutely non-toxic;

 

• hypoallergenic;

 

• produced on the basis of salmon fish milk.

 

Polynucleotides Mastelli – building material for your own skin cells.

 

Plinest Fast is for: 

• prevention of age-related changes;

 

• young skin exposed to stress of various etiologies;

 

• correction of age-related changes in delicate areas (around the eyes, neck, décolleté, hands);

 

• photoaging therapy;

 

• scalp (with diffuse telogen androgenetic hair loss, traction alopecia, eyebrows and eyelashes).

 

Read also:

Delicate skin – special care: the best products for the eye area The drug stimulates fibroblasts well, but gives a minimal moisturizing effect. Ideal for patients aged 25–35 years. 

2. Plinest

 

This is a broad-spectrum bioreparant consisting of highly purified long-chain polynucleotides of natural origin at a concentration of 20 mg/ml.   

 

• correction of pronounced age-related changes;  • deep wrinkles of various origins;

 

• stretch marks and scars.

 

Introduction areas:

 

• face;  • neck;

 

• the back of the hands.

 

The maximum concentration of PDRN simultaneously stimulates the activity of fibroblasts, ensures the growth of new vessels and restores normal tissue microcirculation, activates regenerative processes, restructures the fiber frame of the reticular dermis.

 

Read also:

How to maintain the beauty of the skin in the modern world

 

Gives good results with severe laxity, ideal for patients 45+. In parallel, patients are prescribed home care products that restore the epidermal barrier. 

Plinest Fast polynucleotides to stimulate the growth of eyebrows and eyelashes In what cases is Plinest Fast (Mastelli) polynucleotide therapy effective for stimulating the growth of eyebrows and eyelashes: 

• if the eyebrows are plucked and have not grown in certain areas for a long time;

 

• if the eyelashes become thin and short after a long extension.

 

Disruption of growth and reduction in the thickness and length of hairs on the eyebrows and eyelashes – an urgent problem of modern women who have followed fashion trends for many years.

 

PDRN stimulate angiogenesis, thereby improving nutrition and oxygenation, relieve inflammation and serve as building blocks for cell renewal.

 

This results in:

 

• hair enters active growth phase;  • the diameter of the hair increases noticeably.

 

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Perfect care for the skin of the neck and décolleté

 

Revitalization of eyelashes PDRN Plinest Fast. Insertion Technique: • pre-application of topical anesthetic;

 

• for 1 eye 0.2 & ndash; 0.3 ml of the drug;

 

• needle 32–33G, 4mm;

 

• distance – every 0.3 cm;

 

• insertion depth – needle shear;

 

• Stage 1 – micropapular injections along the edge of the eyelid 1 & ndash; 2 mm, injection angle – 45 degrees;

 

• Stage 2 – inter-eyelash.

 

Required course

: minimum 4 treatments once every 7–14 days. 

Plinest Fast Polynucleotides (Mastelli) awaken the hair, improve its quality and enhance growth. 

Eyebrow revitalization PDRN Plinest Fast. Insertion Technique:

 

• pre-application of topical anesthetic; • for 1 eyebrow – 0.5–1 ml of the drug; 

• needle – 32–33G, 4mm;

 

• distance – every 0.5 cm;

 

• Stage 1 – injections throughout the eyebrow to a depth of 3 – 4 mm, injection angle – 45 degrees;

 

• Stage 2 – in places of maximum lack of eyebrow growth, intradermally micropapularly.

 

Required course:

minimum 4 treatments once every 10–14 days. 

It is important to warn the patient that after injections of polynucleotides, it is strongly not recommended to pluck the eyebrows – this may hinder their further growth. Shape correction can be done after 4 treatments with Plinest Fast.  In this case, eyebrow growth is activated and only intensifies over time.

 

Mastelli Polynucleotides (Plinest, Plinest Fast) from

official distributor of

TOTISPHARMA GROUP

are ideal for working in the delicate and sensitive periorbital area and give excellent results in context eyebrow and eyelash growth stimulation that your patients will definitely appreciate!  More interesting videos on our YouTube-channel!