The skin around the eyes is quite thin, it has practically no subcutaneous fatty tissue. In this regard, active facial expressions leads to the early appearance of creases and wrinkles. Another important anatomical feature of the periorbital zone is a small number of sebaceous glands, which leads to insufficient moisture, loss of tissue tone and elasticity.
Injectable Mastelli Plinest Eye from TOTISPHARMA GROUP portfolio is ideal for biorevitalization and bioreparation of the skin around the eyes as with the purpose of correction, and to prevent age-related changes in the skin.
- Key effects of polynucleotides
- Clinically proven effects of polynucleotides
- Biorevitalization and bioreparation with Mastelli PLINEST® eye
- Clinical Trials of Mastelli Polynucleotides PLINEST® eye: results
Key effects of polynucleotides
Polynucleotides stimulate the proliferation of fibroblasts, re-epithelialization of the epidermis, restoration of cartilage and bone tissues. They provide conditions for the formation of a complete network of collagen in the connective tissue, which is essential before using collagen-stimulating drugs.
The possibilities of skin biorevitalization: the return of youth
Polynucleotides activate the growth of the microvasculature by stimulating the synthesis of VEGF (endothelial growth factor), which allows creating a microenvironment for fibroblasts. They have an anti-ischemic effect, contributing to the mobilization of collateral blood flow and reducing tissue energy consumption, which is especially important for accelerated skin recovery.
Polynucleotides can reduce the reaction of soft tissues after injections, reduce pain, redness, which is especially important when combined with negative stimulation procedures (peels).
Polynucleotides provide protection against photodamage, having protective effects on tissues from ultraviolet and ionizing radiation, which is especially important during hyperinsolation.
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The polynucleotide recycling process provides the necessary amount of "building materials" for the synthesis of its own DNA and RNA molecules, which is especially important in tissues subject to accelerated aging.
Clinically proven effects of polynucleotides
Complete healing of damaged skin due to polynucleotides occurs within 72 hours after application.
Polynucleotides 72 hours after damage restore the correct structure of collagen fibers of the dermis. Therefore, they are shown as preparation and for recovery after damaging procedures and in combination with collagen-stimulating drugs.
ABC of the skin for a cosmetologist: the structure of the epidermis
Change at the histological level 30 days after drug administration:
- complete resorption of the product,
- no signs of toxicity/local inflammation.
Clinically proven Biorevitalization and bioreparation with Mastelli Eye
Mastelli PLINEST® eye from TOTISPHARMA GROUP portfolio - injection therapy for periorbital skin biostimulation based on highly purified long-chain polynucleotides HPT™ natural origin in the form of a liquid gel. The drug helps to increase the elasticity and firmness of the skin, even out the relief, brighten the skin of the periorbital zone.
Readings:- age-related changes in the periorbital zone,
- to improve the quality of the skin before the introduction of botulinum toxin,
- before and after plastic surgery (e.g. blepharoplasty),
- before and after laser/plasma (thermal) resurfacing.
Periorbital zone.
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FacebookInsertion Techniques:To improve the quality of the skin - classic subcutaneous injection; micropapular technique.
To strengthen the ligaments - cannula insertion technique; injections to the depth of attachment of
ligaments to the bony edge of the orbit. Clinical studies of polynucleotides Mastelli PLINEST® eye: results
The patients received 4 injections of
Plinest® eyewith polynucleotides at a concentration of 15 mg/2 ml by injection technique using a 37mm cannula, 27G.
• 90% of patients noted an improvement in their skin condition.
• HPT® polynucleotides improve the quality, texture and tone of the skin.
• HPT® polynucleotides reduce superficial wrinkles.
Polynucleotides – rejuvenation at the DNA levelConclusions:• No side effects reported.
• The therapy was well tolerated by the patients.
• Satisfactory results were achieved in the periorbital zone, which is difficult to treat.
Benefits:• High concentration polynucleotides improve the trophism of fibroblasts in the skin of the periorbital zone.
• Micropapules quickly resolve.
• The drug does not cause an allergic reaction.
• The drug does not cause edema, which allows patients to maintain social activity.
Polynucleotideshave a powerful effect on the tissues of the periorbital zone, protecting them from photodamage, providing an anti-ischemic effect, restoring their elasticity and firmness. Mastelli Plinest Eye from the official distributor of TOTISPHARMA GROUP meets all the necessary criteria and is excellent for effective biorepair and restructuring of the skin around the eyes. More interesting stuff on our
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