Patients who have long-term severe atopic dermatitis (eczema) and are taking lifelong pathogenic therapy to reduce inflammation may be candidates for specific immunotherapy (allergic vaccination).
In the article estet-portal.com you can read in detail the clinical case presented at the annual scientific meeting of the American College of Allergy, Asthma and Immunology — ACAAI, which showed that Allergy vaccination has significant benefits in terms of managing eczema, which affects a 48-year-old man.
Atopic dermatitis as a manifestation of polyvalent allergy
Atopic dermatitis is an allergic disease and patients typically have other types of allergies. Symptoms of eczema include severe itching, excessive dryness, flaking, redness and inflammation of the skin, and sleep disturbance due to the pathological manifestations listed above.
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"This man has suffered from severe eczema since childhood," — says MD, ACAAI member and lead author, allergist Anil Nanda. “He has tried many previous treatments over the years, including low and high strength corticosteroid cream, as well as other topical anti-inflammatory and topical moisturizing creams. Biological therapy has been available to treat eczema for about a year and a half. We decided that allergy vaccination might be useful because he also had a polyvalent allergy.
Specific allergy vaccination — modern accessible method of treatment
Vaccines aim to create or enhance immune responses, but are also effective for treating allergies.
Allergy is a hyperimmune response based on the production of immunoglobulin E against harmless environmental antigens, i.e. allergens. However, allergen vaccination, called allergen-specific immunotherapy, is the only disease-modifying allergy therapy with long-term effects.
How allergic dermatosis manifests itself: features of the clinical picture
New characteristics of diagnostics and vaccination against allergies based on recombinant allergen derivatives, peptides and allergen genes have appeared thanks to the identification of molecular allergens.
Molecular allergen-based vaccines can effectively target the immune system and can eliminate the side effects that have so far limited the use of conventional allergen extract-based vaccines.
Major allergy vaccination is on the horizon, which could help fight the allergy pandemic.
Experience with specific immunotherapy in atopic dermatitis
"We did a scratch prick test and found that this person is allergic to dust mites, weeds, trees, grasses, mold, six cats and dogs," — says MD, ACAAI member and co-author, allergist Anita Vasan.
"Because this patient's allergies can be treated with specific immunotherapy, we hypothesized that treating his allergies might also help get rid of his eczema. A year later, he reported a significant improvement in his condition, which was great news. And once he reached a maintenance dose of allergy vaccines, he no longer needed high-strength steroid therapy for eczema."
Eczema is a chronic relapsing disease. New and existing treatments for eczema can reduce the severity of polyvalent allergies and atopic dermatitis.
Thank you for staying with estet-portal.com. Read other interesting articles in the "Dermatology" section. You might be interested in Lifestyles to choose for atopic dermatitis
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